Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of new targeted therapies, giving the reader a clear appreciation of how the theory translates to tackling the disease.
Introduction to “Concepts of Biotechnology” is a short primer on how cells develop and grow. The aim of this book is to provide a gentle exploration of the fundamental concepts in a easy-to-understand format, using examples and key figures for illustration. It is written in a style to help the reader understand the basic principles that inform our current understanding of Biotechnology, at the molecular, cellular and physiological level. The text can be used as a quick revision guide. It would be suitable for anyone, with or without a background in biology.
From genetics to ecology – the easy way to score higher in biology Are you a student baffled by biology? You're not alone. With the help of Biology Workbook For Dummies you'll quickly and painlessly get a grip on complex biology concepts and unlock the mysteries of this fascinating and ever-evolving field of study. Whether used as a complement to Biology For Dummies or on its own, Biology Workbook For Dummies aids you in grasping the fundamental aspects of Biology. In plain English, it helps you understand the concepts you'll come across in your biology class, such as physiology, ecology, evolution, genetics, cell biology, and more. Throughout the book, you get plenty of practice exercises to reinforce learning and help you on your goal of scoring higher in biology. Grasp the fundamental concepts of biology Step-by-step answer sets clearly identify where you went wrong (or right) with a problem Hundreds of study questions and exercises give you the skills and confidence to ace your biology course If you're intimidated by biology, utilize the friendly, hands-on information and activities in Biology Workbook For Dummies to build your skills in and out of the science lab.
Biomedical researches have witnessed huge leaps with rapid development and better understanding of concepts underlying the living process at molecular level. A short yet comprehensive book that covers principles and basic techniques of molecular biology became a necessity to cope with this fast-paced development.
Reproductive biology and Genetic diversity of Terminalia paniculata is designed to serve as a book for researchers in Biotechnology, Botany, Genetics and molecular biology. The book focuses on explaining the both basic and advanced concepts and techniques in reproductive biology, pollination, molecular biology, and genetic diversity and their application thereof. The book provide comprehensive discussions on pollination in tropical trees, nature of pollinators, nectar secretion pattern, breeding system, allozyme diversity and gene flow aspects.
Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials.Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases - from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.- Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one reference work- Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system- Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases- Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays
Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The «epigenome» is a parallel to the word «genome,» and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA and the chromatin proteins that associate with it. Methylation, for example, can silence a nearby gene and seems to be involved in some cancers. Epigenetics is beginning to form and take shape as a new scientific discipline, which will have a major impact on Medicine and essentially all fields of biology. Increasingly, researchers are unearthing links between epigenetics and a number of diseases. Although in recent years cancer has been the main focus of epigenetics, recent data suggests that epigenetic plays a critical role in psychology and psychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences. Discover more online content in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.
A newly revised edition of the standard reference for the field today—updated with new terms, major discoveries, significant scientists, and illustrations Developmental biology is the study of the mechanisms of development, differentiation, and growth in animals and plants at the molecular, cellular, and genetic levels. The discipline has gained prominence in part due to new interdisciplinary approaches and advances in technology, which have led to the rapid emergence of new concepts and words. The Dictionary of Developmental Biology and Embryology, Second Edition is the first comprehensive reference focused on the field's terms, research, history, and people. This authoritative A-to-Z resource covers classical morphological and cytological terms along with those from modern genetics and molecular biology. Extensively cross-referenced, the Dictionary includes definitions of terms, explanations of concepts, and biographies of historical figures. Comparative aspects are described in order to provide a sense of the evolution of structures, and topics range from fundamental terminology, germ layers, and induction to RNAi, evo-devo, stem cell differentiation, and more. Readers will find such features of embryology and developmental biology as: Vertebrates Invertebrates Plants Developmental genetics Evolutionary developmental biology Molecular developmental biology Medical embryology The author's premium on accessibility allows readers at all levels to enhance their vocabulary in their field and understand terminology beyond their specific focus. Researchers and students in developmental biology, cell biology, developmental genetics, and embryology will find the dictionary to be a vital resource.
Advances in molecular technologies over recent years have a profound impact on diagnostic pathology. Molecular biology techniques utilize DNA, RNA, and enzymes that interact with nucleic acids to understand biology at a molecular level. Information derived from genomics and proteomics have permitted improved insights into a range of disorders and have led to improvements in the understanding and classification of many diseases. These advances will provide a complementary approach to traditional methods of histopathological analysis in the future. Molecular analysis will significantly impact three major areas: specific diagnosis, prognosis determination and prediction of response to therapy. The pathologist will continue to play a fundamental, role in diagnosis and will likely be in a pivotal position to guide the implementation and interpretation of these tests as they move from the research laboratory into diagnostic pathology.
According to the growing demand for being familiar with molecular biology, there is a great need for interested reader to know about its basic concepts and terms. The book entitled "Your First Steps to Molecular Biology" targets a wide sector of readers who look for basic knowledge in order to understand complicated points and ambiguous terms in a simple way. Items are introduced in a pattern that gives linked ideas that serve the main subject. The book starts by informing reader the importance and application of molecular biology to different life aspects. It focuses on DNA biochemical structure and properties that allow the organism to save its specie. It also demonstrates different molecular biology terms such as genetic code, code degeneracy, reading frame, Wobble position and the relation between them. The book discusses how the sequences in DNA act as the archive of life secrets. DNA instructs the cell through mRNA during transcription and translation to express different functional activities. It also discusses mRNA processing, protein modifications, DNA duplication and cell division. The book is a trial for declaring most ambiguous concepts and terms in Molecular Biology.
An Introduction to Molecular Evolution and Phylogenetics presents the fundamental concepts and intellectual tools you need to understand how the genome records information about evolutionary past and processes, how that information can be read, and what kinds of questions we can use that information to answer. Starting with evolutionary principles, and illustrated throughout with biological examples, it is the perfect starting point on the journey to an understanding of the way molecular data is used in modern biology.
Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.* This series provides a forum for discussion of new discoveries, approaches, and ideas* Contributions from leading scholars and industry experts* Reference guide for researchers involved in molecular biology and related fields
The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The book deals with What Is Cancer, Profile of a Cancer Cell, How Cancers Spread, Identifying the Causes of Cancer, Chemicals and Cancer, Radiation and Cancer, Infectious Agents and Cancer, Heredity and Cancer, Oncogenes, Tumor Suppressor Genes and Cancer Overview, Cancer Screening, Diagnosis, and Treatment, Preventing Cancer, Main Types of Cancer, Human Carcinogens. For all readers interested in the big picture view of cancer. The text can be used either as a first step towards a deeper understanding of the mechanisms of cancer progression or it can be used as a quick revision guide. It would be suitable for anyone, with or without a background in biology.The book includes many recent and topical references, and is intended to empower the student to move directly into the primary research literature.
Cell and Molecular Biology and Imaging of Stem Cells features original and review articles written by experts who have made significant contributions to stem cell biology and imaging. Chapters cover a broad spectrum of aspects of the field, including Stem cells from the Amniotic Fluid and Placenta, Biomaterials as Artificial Niches for Pluripotent Stem Cell Engineering, Low-Intensity Ultrasound in Stem Cells and Tissue Engineering, Mammalian Neo-Oogenesis from Ovarian Stem Cells, Oct4-EGFP Transgenic Pigs as a New Tool for Visualization of Pluripotent and Reprogrammed Cells, Regulation of Adult Intestinal Stem Cells, Stem Cell Therapy for Veterinary Orthopedic Lesions, Sex Steroid Combinations in Regenerative Medicine for Brain and Heart Diseases, Hair Follicle Stem Cells, The Potential of Using Induced Pluripotent Stem Cells in Skin Diseases, Mitochondrial Differentiation in Early Embryo Cells and Pluripotent Stem Cells, and The Role of Centrosomes in Cancer Stem Cell Functions. Cell and Molecular Biology and Imaging of Stem Cells addresses a wide variety of cell and molecular topics in unprecedented detail, and is a must-read for graduate students and academic and industry professionals in the expanding field of stem cell biology. Reviews new imaging tools and markers for cell and molecular imaging in stem cell biology. Covers novel aspects of stem cell imaging in reproductive biology and stem cell niches Includes chapters on the developing area of centrosome biology as it applies to embryonic and adult stem differentiation
Rin and Ami have been skipping molecular biology class all semester, and Professor Moro has had enough—he's sentencing them to summer school on his private island. But they're in store for a special lesson. Using Dr. Moro's virtual reality machine to travel inside the human body, they'll get a close-up look at the fascinating world of molecular biology. Join them in The Manga Guide to Molecular Biology, and learn all about DNA, RNA, proteins, amino acids, and more. Along the way, you'll see chemical reactions first-hand and meet entertaining characters like Enzyme Man and Drinkzilla, who show how the liver metabolizes alcohol. Together with Ami and Rin, you'll learn all about: The organelles and proteins inside cells, and how they support cellular functions The processes of transcription and translation, and your genes' role in synthesizing proteins The pieces that make up our genetic code, like nucleotides, codons, introns, and exons The processes of DNA replication, mitosis and cytokinesis Genetic technology like transduction and cloning, and the role of molecular biology in medicine Whether you need a molecular biology refresher or you're just fascinated by the science of life, The Manga Guide to Molecular Biology will give you a uniquely fun and informative introduction.