Molecular Markers in Plants surveys an array of technologies used in the molecular analysis of plants. The role molecular markers play in plant improvement has grown significantly as DNA sequencing and high-throughput technologies have matured. This timely review of technologies and techniques will provide readers with a useful resource on the latest molecular technologies. Molecular Markers in Plants not only reviews past achievements, but also catalogs recent advances and looks forward towards the future application of molecular technologies in plant improvement. Opening chapters look at the development of molecular technologies. Subsequent chapters look at a wide range of applications for the use of these advances in fields as diverse as plant breeding, production, biosecurity, and conservation. The final chapters look forward toward future developments in the field. Looking broadly at the field of molecular technologies, Molecular Markers in Plants will be an essential addition to the library of every researcher, institution, and company working in the field of plant improvement.
Functional Biology of Plants provides students and researchers with a clearly written, well structured whole plant physiology text. Early in the text, it provides essential information on molecular and cellular processes so that the reader can understand how they are integrated into the development and function of the plant at whole-plant level. Thus, this beautifully illustrated book, presents a modern, applied integration of whole plant and molecular approaches to the study of plants. It is divided into four parts: Part 1: Genes and Cells, looks at the origins of plants, cell structure, biochemical processes and genes and development. Part 2: The Functioning Plant, describes the structure and function of roots, stems, leaves, flowers and seed and fruit development. Part 3: Interactions and Adaptations, examines environmental and biotic stresses and how plants adapt and acclimatise to these conditions. Part 4: Future Directions, illustrates the great importance of plant research by looking at some well chosen, topical examples such as GM crops, biomass and bio-fuels, loss of plant biodiversity and the question of how to feed the planet. Throughout the book there are text boxes to illustrate particular aspects of how humans make use of plants, and a comprehensive glossary proves invaluable to those coming to the subject from other areas of life science.
Teaching K-12 math becomes an easier task when everyone understands the language, symbolism, and representation of math concepts Published in partnership with SEDL, The Problem with Math Is English illustrates how students often understand fundamental mathematical concepts at a superficial level. Written to inspire ?aha? moments, this book enables teachers to help students identify and comprehend the nuances and true meaning of math concepts by exploring them through the lenses of language and symbolism, delving into such essential topics as multiplication, division, fractions, place value, proportional reasoning, graphs, slope, order of operations, and the distributive property. Offers a new way to approach teaching math content in a way that will improve how all students, and especially English language learners, understand math Emphasizes major attributes of conceptual understanding in mathematics, including simple yet deep definitions of key terms, connections among key topics, and insightful interpretation This important new book fills a gap in math education by illustrating how a deeper knowledge of math concepts can be developed in all students through a focus on language and symbolism.
This self-contained book gives fundamental knowledge about scattering and diffraction of electromagnetic waves and fills the gap between general electromagnetic theory courses and collections of engineering formulas. The book is a tutorial for advanced students learning the mathematics and physics of electromagnetic scattering and curious to know how engineering concepts and techniques relate to the foundations of electromagnetics
The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent that integration, inform the drug research processes that are most relevant to the pharmaceutical and biotechnology industries. The first book to focus on comprehensive systems biology and its applications in drug discovery and development, it offers comprehensive and multidisciplinary coverage of all phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design and execution, as well as the complementary systems approaches that make these processes more efficient. It also provides models for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker identification. Introducing and explaining key methods and technical approaches to the use of comprehensive systems biology on drug development, the book addresses the challenges currently facing the pharmaceutical industry. As a result, it is essential reading for pharmaceutical and biotech scientists, pharmacologists, computational modelers, bioinformaticians, and graduate students in systems biology, pharmaceutical science, and other related fields.
Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.
Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aims to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. Concepts of Combinatorial Optimization, is divided into three parts: On the complexity of combinatorial optimization problems, that presents basics about worst-case and randomized complexity; Classical solution methods, that presents the two most-known methods for solving hard combinatorial optimization problems, that are Branch-and-Bound and Dynamic Programming; Elements from mathematical programming, that presents fundamentals from mathematical programming based methods that are in the heart of Operations Research since the origins of this field.
Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aim to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. Concepts of Combinatorial Optimization, is divided into three parts: – On the complexity of combinatorial optimization problems, presenting basics about worst-case and randomized complexity; – Classical solution methods, presenting the two most-known methods for solving hard combinatorial optimization problems, that are Branch-and-Bound and Dynamic Programming; – Elements from mathematical programming, presenting fundamentals from mathematical programming based methods that are in the heart of Operations Research since the origins of this field.
Encompasses the latest advances in the field. New series editor, Daniel Purich, is a well-known biochemist and enzymologist.
A comprehensive look at empirical approaches to molecular discovery, their relationships with rational design, and the future of both Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery. Logically arranged, this text examines the different modes of molecular discovery, empha-sizing the historical and ongoing importance of empirical strategies. Along with a broad overview of the subject matter, Searching for Molecular Solutions explores: The differing modes of molecular discovery Biological precedents for evolutionary approaches Directed evolutionary methods and related areas Enzyme evolution and design Functional nucleic acid discovery Antibodies and other recognition molecules General aspects of molecular recognition Small molecule discovery approaches Rational molecular design The interplay between empirical and rational strategies and their ongoing roles in the future of molecular discovery Searching for Molecular Solutions covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspectsof molecular discovery, as well as the thought processes behind experimental approaches. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Clear, concise instruction for all CFA Level I concepts and competencies for the 2018 exam The same official curricula that CFA Program candidates receive with program registration is now publicly available for purchase. CFA Program Curriculum 2018 Level I, Volumes 1-6 provides the complete Level I Curriculum for the 2018 exam, delivering the Candidate Body of Knowledge (CBOK) with expert instruction on all 10 topic areas of the CFA Program. Fundamental concepts are explained in-depth with a heavily visual style, while cases and examples demonstrate how concepts apply in real-world scenarios. Coverage includes ethical and professional standards, quantitative analysis, economics, financial reporting and analysis, corporate finance, equities, fixed income, derivatives, alternative investments, and portfolio management, all organized into individual sessions with clearly defined Learning Outcome Statements. Charts, graphs, figures, diagrams, and financial statements illustrate concepts to facilitate retention, and practice questions provide the opportunity to gauge your understanding while reinforcing important concepts. Learning Outcome Statement checklists guide readers to important concepts to derive from the readings Embedded case studies and examples throughout demonstrate practical application of concepts Figures, diagrams, and additional commentary make difficult concepts accessible Practice problems support learning and retention CFA Institute promotes the highest standards of ethics, education, and professional excellence among investment professionals. The CFA Program Curriculum guides you through the breadth of knowledge required to uphold these standards.The three levels of the program build on each other. Level I provides foundational knowledge and teaches the use of investment tools; Level II focuses on application of concepts and analysis, particularly in the valuation of assets; and Level III builds toward synthesis across topics with an emphasis on portfolio management.
The cutting-edge guide on advancing the science of molecular imaging using nanoparticles Nanoplathform-Based Molecular Imaging provides rationale for using nanoparticle-based probes for molecular imaging, then discusses general strategies for this underutilized, yet promising, technology. It addresses general strategies of particle synthesis and surface chemistry, applications in computed tomography optical imaging, magnetic resonance imaging, ultrasound, multimodality imaging, theranostics, and finally, the clinical perspectives of nanoimaging. This comprehensive volume summarizes the opinions of those in the forefront of research and describes the latest developments by emphasizing fundamentals and initiating hands-on application.
This easy accessible textbook provides an overview of solar to electric energy conversion, followed by a detailed look at one aspect, namely photovoltaics, including the underlying principles and fabrication methods. Professor Wolf, an experienced author and teacher, reviews such green technologies as solar-heated-steam power, hydrogen, and «artificial leaf» approaches, as well as nuclear fusion. Throughout the book, carefully chosen, up-to-date examples are used to illustrate important concepts and research tools. The opening chapters give a broad and exhaustive survey of long term energy resources, reviewing current and potential types of solar driven energy sources. The core part of the text on solar energy conversion discusses different concepts for generating electric power, followed by a profound presentation of the underlying semiconductor physics and rounded off by a look at efficiency and third-generation concepts. The concluding section offers a rough analysis of the economics relevant to the large-scale adoption of photovoltaic conversion with a discussion of such issues as durability, manufacturability and cost, as well as the importance of storage. The book is self-contained so as to be suitable for students with introductory calculus-based courses in physics, chemistry, or engineering. It introduces concepts in quantum mechanics, atomic and molecular physics, plus the solid state and semiconductor junction physics needed to attain a quantitative understanding of the current status of this field. With its comments on economic aspects, it is also a useful tool for those readers interested in a career in alternative energy.
Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as «natural products», explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.
When mercenary Wade Wilson learned that he was dying of cancer, he signed up as a test subject for the mysterious Weapon X program. Wade's cancer was arrested via the implanting of a healing factor derived from the mutant known as Wolverine. However, Wilson soon found himself the victim of the cruel experiments of the vile Doctor Killebrew, where he escaped and, assuming the name Deadpool, embarked on a life as an assassin. Marvel Platinum brings you the very best Deadpool adventures from his very first appearance to the present day!