A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.
A well-written, hands-on, single-source guide to the professional practice of civil engineering There is a growing understanding that to be competitive at an international level, civil engineers not only must build on their traditional strengths in technology and science but also must acquire greater mastery of the business of civil engineering. Project management, teamwork, ethics, leadership, and communication have been defined as essential to the successful practice of civil engineering by the ASCE in the 2008 landmark publication, Civil Engineering Body of Knowledge for the 21st Century (BOK2). This single-source guide is the first to take the practical skills defined by the ASCE BOK2 and provide illuminating techniques, quotes, case examples, problems, and information to assist the reader in addressing the many challenges facing civil engineers in the real world. Civil Engineer's Handbook of Professional Practice: Focuses on the business and management aspects of a civil engineer's job, providing students and practitioners with sound business management principles Addresses contemporary issues such as permitting, globalization, sustainability, and emerging technologies Offers proven methods for balancing speed, quality, and price with contracting and legal issues in a client-oriented profession Includes guidance on juggling career goals, life outside work, compensation, and growth From the challenge of sustainability to the rigors of problem recognition and solving, this book is an essential tool for those practicing civil engineering.
Round out your technical engineering abilities with the business know-how you need to succeed Technical competency, the «hard side» of engineering and other technical professions, is necessary but not sufficient for success in business. Young engineers must also develop nontechnical or «soft-side» competencies like communication, marketing, ethics, business accounting, and law and management in order to fully realize their potential in the workplace. This updated edition of Engineering Your Future is the go-to resource on the nontechnical aspects of professional practice for engineering students and young technical professionals alike. The content is explicitly linked to current efforts in the reform of engineering education including ABET's Engineering Criteria 2000, ASCE's Body of Knowledge, and those being undertaken by AAEE, AIChE and ASME. The book treats essential nontechnical topics you'll encounter in your career, like self-management, interpersonal relationships, teamwork, project and total quality management, design, construction, manufacturing, engineering economics, organizational structures, business accounting, and much more. Features new to this revised edition include: A stronger emphasis on management and leadership A focus on personal growth and developing relationships Expanded treatment of project management Coverage of how to develop a quality culture and ways to encourage creative and innovative thinking A discussion of how the results of design, the root of engineering, come to fruition in constructing and manufacturing, the fruit of engineering New information on accounting principles that can be used in your career-long financial planning An in-depth treatment of how engineering students and young practitioners can and should anticipate, participate in, and ultimately effect change If you're a student or young practitioner starting your engineering career, Engineering Your Future is essential reading.
Bioelectronics is a rich field of research involving the application of electronics engineering principles to biology, medicine, and the health sciences. With its interdisciplinary nature, bioelectronics spans state-of-the-art research at the interface between the life sciences, engineering and physical sciences. Introductory Bioelectronics offers a concise overview of the field and teaches the fundamentals of biochemical, biophysical, electrical, and physiological concepts relevant to bioelectronics. It is the first book to bring together these various topics, and to explain the basic theory and practical applications at an introductory level. The authors describe and contextualise the science by examining recent research and commercial applications. They also cover the design methods and forms of instrumentation that are required in the application of bioelectronics technology. The result is a unique book with the following key features: an interdisciplinary approach, which develops theory through practical examples and clinical applications, and delivers the necessary biological knowledge from an electronic engineer’s perspective a problem section in each chapter that readers can use for self-assessment, with model answers given at the end of the book along with references to key scientific publications discussions of new developments in the bioelectronics and biosensors fields, such as microfluidic devices and nanotechnology Supplying the tools to succeed, this text is the best resource for engineering and physical sciences students in bioelectronics, biomedical engineering and micro/nano-engineering. Not only that, it is also a resource for researchers without formal training in biology, who are entering PhD programmes or working on industrial projects in these areas.
A big-picture look at how the latest trends in information management and technology are impacting business models and innovation worldwide With all of the recent emphasis on «big data,» analytics and visualization, and emerging technology architectures such as smartphone networks, social media, and cloud computing, the way we do business is undergoing rapid change. The right business model can create overnight sensations—think of Groupon, the iPad, or Facebook. At the same time, alternative models for organizing resources such as home schooling, Linux, or Kenya's Ushihidi tool transcend conventional business designs. Timely and visionary, Information, Technology, and the Future of Commerce looks at how the latest technology trends and their impact on human behavior are impacting business practices from recruitment through marketing, supply chains, and customer service. Discusses information economics, human behavior, technology platforms, and other facts of contemporary life Examines how humans organize resources and do work in the changing landscape Provides case studies profiling how competitive advantage can be a direct result of innovative business models that exploit these trends Revealing why traditional strategy formulation is challenged by the realities of the connected world, Information, Technology, and the Future of Commerce ties technology to business and social environments in an approachable, informed manner with innovative, big-picture analysis of what's taking place now in information strategy and technology.
A detailed and thorough reference on the discipline and practice of systems engineering The objective of the International Council on Systems Engineering (INCOSE) Systems Engineering Handbook is to describe key process activities performed by systems engineers and other engineering professionals throughout the life cycle of a system. The book covers a wide range of fundamental system concepts that broaden the thinking of the systems engineering practitioner, such as system thinking, system science, life cycle management, specialty engineering, system of systems, and agile and iterative methods. This book also defines the discipline and practice of systems engineering for students and practicing professionals alike, providing an authoritative reference that is acknowledged worldwide. The latest edition of the INCOSE Systems Engineering Handbook: Is consistent with ISO/IEC/IEEE 15288:2015 Systems and software engineering—System life cycle processes and the Guide to the Systems Engineering Body of Knowledge (SEBoK) Has been updated to include the latest concepts of the INCOSE working groups Is the body of knowledge for the INCOSE Certification Process This book is ideal for any engineering professional who has an interest in or needs to apply systems engineering practices. This includes the experienced systems engineer who needs a convenient reference, a product engineer or engineer in another discipline who needs to perform systems engineering, a new systems engineer, or anyone interested in learning more about systems engineering.
Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.
Systems biology is a relatively new biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. Systems biology is the study of the interconnected aspect of molecular, cellular, tissue, whole animal and ecological processes, and comprises mathematical and mechanistic studies of dynamical, mesoscopic, open, spatiotemporally defined, nonlinear, complex systems that are far from thermodynamic equilibrium.
Developmental biology is at the core of biological science, integrating molecular biology, genetics and anatomy. The past 15 years has seen revolutionary advances not only in our understanding of the processes by which an egg develops into an adult, but also in the application of this knowledge to the areas of reproductive technology, drug development and organ replacement. Essential Developmental Biology is a concise and well-illustrated treatment of this subject for undergraduates. Assuming no prior knowledge of anatomy and only the basics of cell biology and genetics, the book starts off by introducing the principles and approaches of developmental biology. The second section covers the characteristic development of each of the principal model species used for research and the final chapters are devoted to organ development, predominantly in vertebrates. With an emphasis throughout on the evidence underpinning the main conclusions, this book is suitable as the key text for both introductory and more advanced courses in developmental biology. A new approach to a widely taught subject. Priced for student purchase at approximately half the price of the main competition. Over 200 illustrations, with artwork available free on the Web. Well-known author/media celebrity.
An expert overview of new technologies guiding the construction of a sustainable society This compendium of important insights from sixty distinguished international scholars looks at the significant advances in progressive environmental technology—especially the molecular engineering used on plants, animals, and microorganisms—as the game changer in the high-stakes race to reverse earth-damaging practices. Biocatalysis and Biomolecular Engineering covers subject matter on the latest developments in eco-friendly and energy-saving manufacturing processes with the emphasis on agricultural technology and bio-based products. Focusing its study on remedies that show promise in curing food and energy ills, this book examines groundbreaking work in various fields, such as nutraceuticals, genetic engineering of agricultural products, and bioenergy. Biocatalysis and Biomolecular Engineering: Can be used as a reference by teachers, graduate students, and industrial scientists who conduct research in bioscience and biotechnology Serves as the first book to bring together fundamentals and leading-edge technologies for the development of bio-based industrial products through biocatalysis; for example, it discusses the preparation of biofunctional micro- and nanoparticles Contains chapters by international experts from academia, industry, and government research institutes Biocatalysis and Biomolecular Engineering builds a cohesive, well thought out case for nurturing new discoveries in eco-technology by inviting critical discussion on devising viable solutions to sustaining the future wellness of humankind.
Reproductive Biology of Teleost Fishes is the first integrated review of the reproductive biology of the bony fishes, which are the most species-rich and diversified group of vertebrates. Teleosts display remarkable variation in their modes of reproduction, and this volume is intended to provide a framework for understanding the remarkable reproductive diversity of this group. It describes their reproductive biology using, wherever possible, phylogenetic analyses and life-history theory as a means to interpret the information. The book addresses the genetic, physiological, behavioural, ecological, evolutionary and applied aspects of teleost reproduction in a comparative framework that emphasises the adaptive basis of reproductive diversity. Reproductive Biology of Teleost Fishes provides a comprehensive synthesis of fish reproduction that will be of great interest to life scientists, particularly ecologists, evolutionary biologists, physiologists and advanced undergraduates, postgraduates and research workers requiring a comprehensive overview of fish reproduction. The book is suitable for courses in fish biology and ecology, reproductive physiology and reproductive genetics. It also addresses applied questions and will be of value for courses on fisheries science and aquaculture. Libraries in all universities and research establishments where biological sciences, fisheries science and aquaculture are studied and taught should have several copies of this important book on their shelves.
Systems engineering is the design of a complex interconnection of many elements (a system) to maximize a specific measure of system performance. It consists of two parts: modeling, in which each element of the system and its performance criteria are described; and optimization in which adjustable elements are tailored to allow peak performance. Systems engineering is applied to vast numbers of problems in industry and the military. An example of systems engineering at work is the control of the timing of thousands of city traffic lights to maximize traffic flow. The complex and intricate field of electronics and computers is perfectly suited for systems engineering analysis and in turn, advances in communications and computer technology have made more advanced systems engineering problems solvable. Thus, the two areas fed off of one another. This book is a basic introduction to the use of models and methods in the engineering design of systems. It is aimed at students as well as practicing engineers. The concept of the «systems of systems» is discussed extensively, after a critical comparison of the different definitions and a range of various practical illustrations. It also provides key answers as to what a system of systems is and how its complexity can be mastered.
A newly revised edition of the standard reference for the field today—updated with new terms, major discoveries, significant scientists, and illustrations Developmental biology is the study of the mechanisms of development, differentiation, and growth in animals and plants at the molecular, cellular, and genetic levels. The discipline has gained prominence in part due to new interdisciplinary approaches and advances in technology, which have led to the rapid emergence of new concepts and words. The Dictionary of Developmental Biology and Embryology, Second Edition is the first comprehensive reference focused on the field's terms, research, history, and people. This authoritative A-to-Z resource covers classical morphological and cytological terms along with those from modern genetics and molecular biology. Extensively cross-referenced, the Dictionary includes definitions of terms, explanations of concepts, and biographies of historical figures. Comparative aspects are described in order to provide a sense of the evolution of structures, and topics range from fundamental terminology, germ layers, and induction to RNAi, evo-devo, stem cell differentiation, and more. Readers will find such features of embryology and developmental biology as: Vertebrates Invertebrates Plants Developmental genetics Evolutionary developmental biology Molecular developmental biology Medical embryology The author's premium on accessibility allows readers at all levels to enhance their vocabulary in their field and understand terminology beyond their specific focus. Researchers and students in developmental biology, cell biology, developmental genetics, and embryology will find the dictionary to be a vital resource.
Doing business in the digital age The Great Fragmentation: And Why the Future of All Business is Small is a business survival manifesto for the technology revolution. As the world moves from the industrial era to the digital age, power is shifting and fragmenting. Power is no longer about might and ownership; power in a digital world is about access. Existing businesses need to understand this shift and position themselves to survive and thrive in an environment where entrepreneurs and start-ups enabled by access to technology are genuine threats. Author Steve Sammartino is widely regarded as a thought leader on the subject of technology and business, and helps companies transition from industrial-era thinking to the mindset and processes required to compete in today's digital marketplace. The Great Fragmentation shows how technological changes such as Big Data, gamification, crowdfunding, Bitcoin, 3D printing, social media, mashup culture and artisanal production will forever change business and the way we live our lives. Examine how the digital era has altered where we work, how we work, where we live and what we do Discover how the digital era has impacted social and economic structures, including educational systems, financial systems and government policy Understand that the social media and collecting 'friends' is just the tip of the iceberg in a digital business environment Weaving together insights from business, technology and anthropology, The Great Fragmentation provides both corporations and entrepreneurs with a playbook for the future of work, life and business in the digital era.
Since the technology has moved strongly into a number of different areas a textbook of this sort could be used by a wide variety of academic departments including physics, electrical engineering, mechanical engineering, civil engineering, aerospace engineering and bioengineering. To make the second edition as widely appealing as possible a series of significant upgrades were made. 1. The book is structured to support a variety of academic programs and it can also be used as a general reference by practicing engineers and scientists. 2. The introductory chapter has been revised to outline the new content of the second edition and provide a overview of the current status of fiber optic sensor technology. 3. A new, extensive chapter has been added covering fiber optic grating sensor technology and its application to aerospace, civil structures, oil and gas and power generating applications. 4. A second new chapter has been added on the emerging field of biomedical fiber optic sensors. This is one of the most rapidly growing fields of use for fiber optic sensors and with rising health costs and medical advances promises to be an important area for many years to come.