The book represents the English version, with modifications and additions, of the university course entitled "Kinetotherapy in cardiovascular diseases" published by “Alexandru Ioan Cuza” University Publishing House, Iasi, Romania, in 2014, the author Bogdan-Alexandru Hagiu. Is addressed to physical therapy specialists, providing basic information about cardiovascular diseases and their possible treatments. The last chapter, "The role of isometric contractions in treating cardiovascular disease" includes therapeutic applications of barbell-expander devices, invented by the author.
Role of ubiquitin has been observed in cardiovascular diseases. An overview of the various ubiquitin ligases involved in cardiovascular diseases is given. Their structure in Cn3D is also shown. This book aims at proposing models using ubiquitin which might be worked upon later and research can be carried out on those which could prove very beneficial in the future in treatment or prevention of cardiovascular diseases.
Cardiovascular disease is one of the leading causes of death in the world and the number of patients increases worldwide. To investigate the cardiovascular disease in early stage, reliable model predictions are required. In computational cardiovascular models parameters are one of the major sources of uncertainty, which make the models unreliable and less predictive. In order to achieve predictive models that allow the investigations of the cardiovascular diseases, sensitivity analysis (SA) can be used to quantify and reduce the output uncertainty caused by model parameters.
This book entitled "Impact of Heart Friendly Mix on Cardiovascular Patients" provides you the details on the prevalence of Cardiovascular Diseases in the targeted area. It also provides you the demographic profile and nutritional status of the Cardiovascular patients. This book gives information on the effect of selected heart friendly foods on the lipid profile of selected cardiovascular patients.
Cardiovascular diseases are the leading cause of death in patients on chronic dialysis. Numerous epidemiologic researches have proved a significant frequency of cardiovascular diseases in patients with chronic kidney disease. Multicentric studies have shown great incidence of cardiovascular complications in patients on dialysis. Patients with chronic kidney diseases have 10-20 times greater risk of developing cardiovascular disease in comparison to general population. Risk for starting cardiovascular diseases can be differentiated in patients on continuous ambulatory peritoneal dialysis and patients on hemodialysis, especially in patients who remain on peritoneal dialyses for more than two years and loose the remaining kidney function. Part of cardiovascular damage in patients treated with dialyses is caused by the use of residual renal therapy and question which therapy is more harmful, hemodialysis or peritoneal is very important. Despite the importance of the subject only several studies have been done in comparing cardiovascular test of patients treated with peritoneal dialyses and patients treated by hemodialysis. Our research deals with this issue in particular.
The association between dental and cardiovascular diseases appears to be indirect or circumstantial and the results from previous studies connecting dental diseases to cardiovascular diseases are inconsistent. The aim in this cross-sectional study was to investigate whether there are associations between dental and cardiovascular diseases when adjusted for other predictors. This study indicated that the number of missing teeth showed a possible association with history of stroke. Number of carious tooth surfaces and gingival bleeding were found to be associated with history of congestive heart failure. Heart attack was shown to be associated with the number of missing teeth; in the sub-sample, heart attack did not show an association with any of the dental diseases. Association between periodontal pockets and cardiovascular diseases was not shown in this study. Additional studies are suggested to determine the nature of the relationship between the oral and cardiovascular diseases. Laboratory measures of infection and clinical evaluations should be used in longitudinal studies for further investigations.
In the developed world, life expectancy has increased substantially during the last century. Deaths due to infectious diseases also declined in these countries whereas deaths due to cancer and other cardiovascular diseases increased. With the rising socio-economic status, similar health transition is occurring in some of the developing countries. In India, though infectious diseases continue to be a public health problem but an increase in the occurrence of non-communicable diseases has also been noted particularly in urban areas and in economically advanced states.
Cardiovascular diseases are leading causes of death worldwide. Many efforts have been paid on understanding the underlying mechanisms and causes. However, identifying their risk factors and individual impacts on the diseases onset and progression might be the most effective ways, since specific solutions and treatments can be applied. Survival analysis is a statistical method and approach to identify potential factors and also their effects. Furthermore, it provides the power to predict when cardiovascular diseases might occur given those potential risk factors. This book introduces theories and methods of survival analysis, and also offers some mathematical deductions for conclusions. Therefore, it can be used as a reference book for senior undergraduates and graduates who are interested in the field. In addition, it also describes detail procedures for analysis.
Medical survey and studies highlights cardiovascular diseases as the prime cause for the loss of human lives. Overall impact of the cardiovascular diseases results in sublime demands for attention towards the objective of having early, quick and reliable identification of the symptoms. The advances in the field of technology have offered a platform over which one of the biggest challenges of the medical sciences can be analyzed for better solutions. The electrocardiogram (ECG), used for pre-diagnosis of the cardiovascular diseases, signifies the scope of technology and its involvement in medical sciences. For the measurement or understanding of electrical impulses and their activity in the heart ECG can be used. Electrocardiogram will be effectively used for non evasive detection of the vas diseases.This project avails the capability of Artificial Neural Network Techniques or ANN to analyze information of the patient records suffering from cardiovascular diseases & draws classification, that whether the patient is suffering from arrhythmia or not.
Cardiovascular diseases remain a paramount focus of basic and clinical investigation. They are the leading cause of death in developed countries and their prevalence is increasing in the developing countries. Early detection of the formation and progression of atherosclerotic plaques is therefore essential. Proteomics is a tool designed to address this need at the level of signal transduction, organelle and cellular mechanism and biomarker development. This review examines the increasing use of traditional and novel biomarkers that are transforming cardiovascular medicine.
The Habilitation work reflects the author's activity performed between 2005 and 2013 years, after PhD work, and it is based on the original contributions achieved during research activities in the Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of Romanian Academy. Also, there are highlighted author’s managerial competence and presentation ability. The author’s researches in the field of cardiovascular disease bring new scientific contributions for a better understanding of the vascular dysfunction, cardiovascular risk factors, cellular and molecular biomarkers and corresponding therapy. The original articles are in the field of endothelial function/dysfunction, endothelial vasoactive factors, microparticles (MPs) and endothelial progenitor cells (EPCs) as a signature of vascular dysfunction and a repair mechanism in cardiovascular diseases. Also, the effect of some drugs as enoxaparin, nebivolol, irbesartan on the endothelial dysfunction were intensively investigated.
The metabolic syndrome (MS), also known as syndrome X, was described in 1988 as a special pathological entity among the metabolic diseases by Gerald Raven. By its very existence it drew the attention of numerous researches all over the world. The large interest that this mysterious named entity has caused can be understood by the influence of its components that are the leading diseases of the modern civilization, such as the disorder in the glucose metabolism, fats, hypertension and the increased development of cardiovascular diseases because of increased process of atherosclerosis.
Blood pressure variability (BPV) is one of the recognized risk factor for different types of cardiovascular diseases. In recent times there has been an alarming increase in the incidence of hypertension and cardiovascular diseases (CVD) in India. It is presumed that the phenomenon could be attributed to concomitant prevalence of abnormality in the blood pressure variability (BPV). We aspire that the results obtained and documented in this work will provide the scientific community with the novel data on BPV in human population of India that has never been studied earlier. In addition, a comparative account of BPV among healthy and hypertensive subjects may contribute significantly to the existing knowledge on the discipline. The outcome of the study might help in: (a) establishing the standard values of blood pressure and heart rate with special reference to gender and age, (b) assessing the relative role of predictors of hypertension, and (c) delineating plans to curb various cardiovascular diseases in India.
Cardiovascular disease is today the largest single contributor to global mortality. A major challenge in human health over the next 50 years is to reduce the impact of chronic diseases. The health benefits of a diet rich in fruits, vegetables and legumes have been well recognized. Poor compliance to dietary recommendations, unhealthy lifestyle and mismanagement of cardiovascular emergencies reflect the dearth of awareness among the community. This book provides data on the nutritional, cardiovascular and biochemical profile of adults living with cardiovascular disease in the ‘Temple Town’ of Tamil Nadu, Madurai with lucid and interesting illustrations. An attempt has been made to associate these factors along with their critical energy balance with cardiovascular disease. Specific focus has also been on the occurrence of various metabolic syndrome components and cardiovascular disease. This book can adorn the bookshelf of academicians, researchers, nutritionists and scholars interested in clinical nutrition.
The most significant role of the drug statins in the reduction of serum lipids has been well recognized in both primary and secondary prevention studies. However, after proven its efficacy statins remain underutilized in numerous settings. Recently, studies are suggesting that statins might positively impact many organs systems and disease states independent of lipid reduction, has appeared and their anti-inflammatory effects have also been investigated. Atorvastatin is one of the most widely prescribed statin in the world. The statin-mediated anti-inflammatory effects in addition to its lipid lowering properties and also reduces the risk for cardiovascular diseases. It is to be highlighted that the drug atorvastatin, has multiple effects on different pathways of the multifactorial etiology of cardiovascular diseases. This is supporting the practice of early introduction of atorvastatin in high-risk patients.