Systems biology is a relatively new biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. Systems biology is the study of the interconnected aspect of molecular, cellular, tissue, whole animal and ecological processes, and comprises mathematical and mechanistic studies of dynamical, mesoscopic, open, spatiotemporally defined, nonlinear, complex systems that are far from thermodynamic equilibrium.
This book provides a rigorous algebraic study of the most popular inference formalisms with a special focus on their wide application area, showing that all these tasks can be performed by a single generic inference algorithm. Written by the leading international authority on the topic, it includes an algebraic perspective (study of the valuation algebra framework), an algorithmic perspective (study of the generic inference schemes) and a «practical» perspective (formalisms and applications). Researchers in a number of fields including artificial intelligence, operational research, databases and other areas of computer science; graduate students; and professional programmers of inference methods will benefit from this work.
Structural dynamics is a subset of structural analysis which covers the behavior of structures subjected to dynamic loading. The subject has seen rapid growth and also change in how the basic concepts can be interpreted. For instance, the classical notions of discretizing the operator of a dynamic structural model have given way to a set-theoretic, function-space based framework, which is more conducive to implementation with a computer. This modern perspective, as adopted in this book, is also helpful in putting together the various tools and ideas in a more integrated style. Elements of Structural Dynamics: A New Perspective is devoted to covering the basic concepts in linear structural dynamics, whilst emphasizing their mathematical moorings and the associated computational aspects that make their implementation in software possible. Key features: Employs a novel ‘top down’ approach to structural dynamics. Contains an insightful treatment of the computational aspects, including the finite element method, that translate into numerical solutions of the dynamic equations of motion. Consistently touches upon the modern mathematical basis for the theories and approximations involved. Elements of Structural Dynamics: A New Perspective is a holistic treatise on structural dynamics and is an ideal textbook for senior undergraduate and graduate students in Mechanical, Aerospace and Civil engineering departments. This book also forms a useful reference for researchers and engineers in industry.
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Introduction to Private Equity is a critical yet grounded guide to the private equity industry. Far more than just another introductory guide, the book blends academic rigour with practical experience to provide a critical perspective of the industry from a professional who has worked at many levels within the industry, including insurance, funds of funds, funds and portfolio companies. The book looks at private equity from the point of view of the individual or the business. How is a private business valued? How is the acquisition transaction processed? What are the due diligence issues that should be considered before moving ahead? A valuable insight to a rather opaque market. Introduction to Private Equity covers the private equity industry as a whole, highlighting its historical development in order to put its recent development into perspective. The book covers its organization, governance and function, then details the various segments within the industry, including LBO, Venture Capital, Mezzanine Financing, Growth Capital and beyond. Finally, it offers a framework to anticipate and understand its future developments. It provides a balanced perspective on the current corporate governance challenges which are affecting the industry and draws perspective to understand the evolution of the sector, following one of its major crises.