rtation results showed that the test extract recovers the blood parameter in curative and preventive study, while mechanistic study showed protection of RBC membrane when exposed to ruinous substances. Thus, present finding affirm assentation of this plant in folk medicine for the management of hemolytic anemia.Traditional oral report indicates that fruits of opuntia ficus indica are used in the treatment of anemia in India. It is cheaper and widely available plant. The claims reported in favour of opuntia ficus indica are not substained by modern scientific studies. For this purpose, the present study was carried out to validate effect of dehydrated water extract of opuntia ficus indica on experimentally-induced hemolytic anemia in rats. In mechanistic study, the protective actions of test extract on red blood cells against hypotonic solution, verapamil and calcium free medium was evaluated. Present book results showed that the test extract recovers the blood parameter in curative and preventive study, while mechanistic study showed protection of RBC membrane when exposed to ruinous substances. Thus, present finding affirm assentation of this plant in folk medicine for the management of hemolytic anemia.
The present investigation was developed to evaluate the ethnopharmacological activities of some members of family Moraceae. The selected plants were Ficus bengalensis, Ficus religiosa, Ficus glomerata, Morus indica and Morus laevigata. Ethnopharmacological activities were carried out by the preparation of aqueous and methanolic extracts of different parts of these selected plants. For ethnopharmacological activities, the dried leaves of Ficus bengalensis, Ficus religiosa and Ficus glomerata, dried fruits and leaves of Morus indica and Morus laevigata were extracted with water and methanol for anti-emetic activity anthelmintic, antiallergy and antibacterial activities.
This book gives detailed idea of effect of air pollution on roadside plants in major cities of India, a case study being Pune city. In this work plant morphological, anatomical, physiological and biochemical response of naturally growing roadside plants viz., Polyalthia longifolia, Ficus benjamina and Mangifera indica were investigated. Along with this, special stress was given on plant anatomical changes.
Family Moraceae comprises over fifty genera and nearly 1400 species distributed in temperate, tropical and subtropical regions of America, Africa, Asia and Australia, including such important groups as Artocarpus, Morus and Ficus. Ficus, the fig genus, alone consists of over 800 species. Many Ficus spp. had been widely used in folk medicine, ancient and medieval medicaments for treatment of cancer,inflammation and as antioxidants. Ficus sycomorus L. was used by Ibn sina as poultice of fresh/dried fruit for splenomegaly treatment. Morus fruits, roots and bark have been used in folk medicine (especially in Chinese medicine) to treat diabetes, hypertension, anemia and arthritis. The plants under investigation are : Morus alba L., Morus nigra L. , Ficus sycomorus L., Ficus lyrata Warb. ,Ficus religiosa L., Ficus racemosa L., Ficus mysorensis Roth.,Ficus macrocarpa Hugel,Ficus microcarpa L. and Ficus cunninghami Miq. These plants are evaluated as antioxidants and hypolipidemic agents.
This book discuss the effect of some known hemolytic/oxidant agents on uremic patient's RBCs in vitro, and the effect of some known medicinal plants on reduction of hemolysis (in vitro) and in decreasing of blood urea levels in vivo. Also made a comparison between normal TAC (total antioxidant capacity) and uremic patients Total antioxidant capacity of both (newly diagnosed & patients under dialysis).
Sickle cell disease is an inherited blood disorder characterized by a chronic hemolytic anemia that contributes to painful crises. It is an autosomal recessive disorder caused by production of abnormal hemoglobin S and is associated with high morbidity and mortality. It may influence the quality of life of children, who may require more frequent hospital care. Quality of life refers to people’s ability to function in the ordinary tasks of living. It moves beyond direct manifestations of illness to the patient's personal morbidity.
This book focusses on the pharmacological and toxicological investigations of Saraca indica (Family :Caesalpiniaceae) , a well known plant in the Indian traditional medicinal system. The present investigation deals with the toxicological and biochemical evaluation of the alcoholic extract of bark of Saraca indica through acute and subacute toxicity studies. Also, The antidepressant and oestrogenic activities were evaluated. In addition, genotoxic assays were carried out to assess the effect of Saraca indica bark extract in swiss albino mice.
Excipients are additives, used to convert active pharmaceutical ingredients into pharmaceutical dosage form suitable for administration to patients. New and improved excipients continue to be developed for conventional drug delivery systems and also to meet the needs of modern and better formulations. Mucilages are most commonly used adjuvants in the manufacturing of different pharmaceutical dosage forms. They possess variety of pharmaceutical applications with suspending agent property among others. The natural sources, but not limited to, for mucilage are different species of cactus, a plant that belongs to cactaceae family, which grows in arid and semi arid regions of the globe. This book, hence, compares the physicochemical properties of mucilages extracted from Opuntia ficus indica and Opuntia Strica species of cactus. Moreover, it evaluates the effect of electrolyte, pH and concentration of mucilage on the suspending ability of the extracted mucilages, as compared with sodium carboxylmethyl cellulose as reference suspending agent, in paracetamol suspension.
Opuntia species (Cactaceae) are a well known and important plant widely used in several indigenous system of medicine for the treatment of various ailments, viz. asthma, inflammatory diseases, ulcer and diabetes. Betalains and phenolic compounds have been reported as the major phytoconstituents of this species. The various analytical methodologies were used for the analysis of betalains in Opuntia species. Different pharmacological experiments in a number of in vitro and in vivo models have convincingly demonstrated the ability of Opuntia species to exhibit various pharmacological activities, leading support to the rational behind several of its traditional uses. Due to remarkable biological activity of Opuntia and its constituents, it will be appropriate to develop them as a medicine. The review summarizes a comprehensive knowledge on phytochemical compositions, analysis of betalains and ethnopharmacological actions of Opuntia species.
The book describes effects of air pollutants on some plants studied at four residential and seven commercial locations. The effect of four air pollutants namely SPM, RSPM, SOx and NOx were ascertained on Azadirachta indica, Cassia fistula, Ficus religiosa, Delonix regia and Polyalthia longifolia plants growing on road sides at 11 selected locations with a control (non-polluted) site. Variation in concentrations of these pollutants in relation to years, seasons and locations is explained with appropriate statistical treatment. Effect of air pollutants on plants have been given in terms of changes in leaf characters of different plant species as compared to reference site. The publication contains computation of Air Pollution Tolerance Index and its use in identification of relative tolerance of plant species. Best Subsets Linear Regression technique was used to identify the major pollutants influencing various leaf characters in different species and develop a model to predict the effect of air pollutants on plants. In the light of findings appropriate mitigation measures have been suggested.
Dillenia indica Linn, commonly known as Chalta, is abundantly available almost all over Bangladesh. The present study was carried out to evaluate the anti-diabetic and anti-hyperlipidemic properties of Dillenia indica on type 2 diabetic model rats. A single intraperitoneal (i.p) dose of chloroform fraction (200 mg/ kg body weight) of methanol extract of Dillenia indica fruit significantly reduced fasting blood glucose (FBG) level on alloxan induced diabetic rats. The most significant reduction of FBG level (65%) after 50 hour of administration. This effect almost similar to that of standard drug metformin (150 mg/kg b.w.). In alloxan induced diabetic rat, the total cholesterol and serum triglyceride levels were increased by 49 and 41%, respectively. Chloroform fraction of fruit also reduced the total cholesterol and serum triglyceride level 60 and 55%, respectively on alloxan induced rat. On the hand, CHCl3 fraction of D. indica bark at early phase reduced the blood glucose level and and later at 50 hour it increased to 30%, meanwhile increased 28 and 54% of TC and TG level, respectively on alloxan induced rat.
This book is based on the role of co-morbid disorder; beta thalassemia minor with iron deficiency anemia in the promulgation of beta thalassemia gene. This book explain the pathophysiology of co-morbid condition and its effect on hematological parameters and Hb-A2 levels. This book is useful for the medical students, general physicians,consultant hematologist and Pathologist. In the areas where beta thalassemia is more common genetic disorder this book will proved as useful tool to stop the propagation of beta thalassemia gene in homozygous state.
Experiments were carried out to study the effect of six selected plant extracts viz., Calotropis procera, Azadirachta indica leaf and seed kernel, Allium sativum bulb, Withania somnifera leaf and Solanum suratteuse green berry on mycelial growth and spore germination of Alternaria brassicae in vitro. Influence of these extracts used as foliar sprays on host defense related biochemical parameters i.e. soluble phenol, sugar and protein content, peroxidase, polyphenol oxidase and phenylalanine ammonia lyase activities in mustard leaves was observed. The effect of plant extracts on intensity of Alternaria blight and seed yield in mustard was also recorded. The results revealed that all the six plant extracts Calotropis procera, Azadirachta indica leaf extract, A. indica seed kernel, Allium sativum bulb, Withania somnifera leaf and Solanum suratteuse green berry prepared in distilled water, acetone or methanol, significantly inhibited the mycelial growth and spore germination of A. brassicae at 5, 10 and 15 per cent concentrations in potato dextrose agar medium. The aqueous extract of A. indica seed kernel was most inhibitory to mycelial growth and spore germination of A. brassicae.
The association between Anemia of Chronic Disease (ACD)and chronic periodontitis has been studied with varying results .In the earlier studies it was reported that anemia plays a direct role in the etiology of periodontal disease . On the contrary, it has been demonstrated that anemia occurred as a result of destructive periodontal disease by means of chronic inflammation.This separate entity was termed as Anemia of Chronic Disease.Therefore in the present study, an attempt was made to explore a link between chronic periodontitis and anemia of chronic disease by evaluating certain hematologic markers indicative of ACD .
Conventional plants are precious source of novel cytotoxic agents and are still in performance better role in health concern. The study was intended to estimation of the anticancer activity of Methanolic Extract of Aristolochia indica on human chronic mylogenous leukemia cancer cell lines. Extract was tested for its inhibitory effect in 96 micro plate formats against K562 Cell Line. Plant gave good apoptotic DNA fragmentation. Summaries the data of the activities on in-vitro screening of Aristolochia indica plant extract, its gave positive activity on Cytotoxicity and Antimicrobial activity. The plant also gives Antimutagenic activity concluded from mutation study.