The principles of drug therapies are fundamental to medical practitioners in all branches; but are often difficult to get to grips with. Prescribing at a Glance addresses the most common uses of prescription drugs, and follows progress from dose calculation, administration to monitoring the effects in the treatments of major presenting problems. With a focus on prescribing, this user-friendly guide helps practitioners to develop crucial knowledge and skills, including establishing accurate drug histories, planning appropriate therapies, writing safe and legal prescriptions, critically appraising the prescribing of others, patient support, accessing reliable information about medicines, and detecting adverse drug reactions. Prescribing at a Glance:: Features detailed and high-quality colour illustrations throughout Includes examples of common prescribing errors, practice prescriptions and calculations Follows the structure of the WHO Good Prescribing Guide, and corresponds to the core curriculum of the British Pharmacological Society Is the perfect guide to help you prepare for the Prescribing Skills Assessment (PSA) Includes a companion website featuring interactive MCQs and cases, available at www.ataglanceseries.com/prescribing From the series that brought you Medical Pharmacology at a Glance, and designed to help those in the later stages of their medical training become adept at the skills required for a vital yet often confusing subject – Prescribing at a Glance will help you fill in any knowledge gaps with simple step-by-step instructions, and clear, easy-to-remember guidelines.
Strategize, plan, and execute comprehensive drug-drug interaction assessments for therapeutic biologics Offering both theory and practical guidance, this book fully explores drug-drug interaction assessments for therapeutic biologics during the drug development process. It draws together and analyzes all the latest findings and practices in order to present our current understanding of the topic and point the way to new research. Case studies and examples, coupled with expert advice, enable readers to better understand the complex mechanisms of biologic drug-drug interactions. Drug-Drug Interactions for Therapeutic Biologics features contributions from leading international experts in all areas of therapeutic biologics drug development and drug-drug interactions. The authors' contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience. Coverage includes such essential topics as: Drug-drug interaction risks in combination with small molecules and other biologics Pharmacokinetic and pharmacodynamic drug-drug interactions In vitro methods for drug-drug interaction assessment and prediction Risk-based strategies for evaluating biologic drug-drug interactions Strategies to minimize drug-drug interaction risk and mitigate toxic interactions Key regulations governing drug-drug interaction assessments for therapeutic biologics. Drug-Drug Interactions for Therapeutic Biologics is recommended for pharmaceutical and biotechnology scientists, clinical pharmacologists, medicinal chemists, and toxicologists. By enabling these readers to understand how therapeutic biologics may interact with other drugs, the book will help them develop safer, more effective therapeutic biologics.
‘This remarkably comprehensive book reflects the depth of knowledge and experience of its author and will assist nurses in the process of diabetes management. I wholeheartedly recommend this text to all health professionals whether working directly in, or on, the fringe of diabetes. ‘ From the foreword by Marg McGill, Chair, International Diabetes Federation Consultative Section on Diabetes Education Care of People with Diabetes is an essential guide to the care and management of people with diabetes mellitus, with particular emphasis on the acute care setting. It is written by an experienced clinical nurse specialist with extensive knowledge of evidence-based diabetes care. The book serves as an essential companion to clinical practice for nurses and health professionals. This third edition of Care of People with Diabetes has been extensively revised, and includes new information on smoking cessation, diabetes and driving, coeliac disease and Polycystic Ovarian Syndrome. Key features: Fully revised new edition of a successful text Provides the evidence for best practice Includes protocols for consistent care and improvement of patient outcomes Each chapter includes lists of key points, boxes highlighting key information, further reading, patient information, and patient care sheets.
A clear explanation of the cause, diagnosis, and treatment of diabetes Written for a broad range of readers, including students, researchers, policymakers, health care providers, and diabetes patients and caregivers, this book explains the underlying biochemistry and physiology of diabetes mellitus. Each chapter contains a glossary that defines key terms, a summary that highlights essential concepts discussed in each section of the chapter, as well as a set of simple problems to help readers gain a richer and deeper understanding of diabetes, from its history to treatment options. Understanding Diabetes begins with an overview of the disease, its worldwide prevalence and cost, and its connection to the global obesity epidemic. The author then explores the history of diabetes, including the first documented description of the disease dating back to 3400 BCE in Ancient Egypt. The next chapter, A Glucose Metabolism Primer, sets forth the pathways for the metabolism of glucose. Next, the book covers: Regulation of glucose metabolism and glucose metabolism gone wrong Diabetes classification system Diagnosis, including current laboratory tests Complications, such as retinopathy, neuropathy, and cardiovascular disease Hereditary transmission Prevention and treatment, including emerging research Although a cure has still not been found, this book demonstrates that researchers are continuing to make major breakthroughs on all fronts in the fight against diabetes, including a better understanding of its causes and an improved ability to diagnose and treat the disease.
The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.
The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs. Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.
Clinical Pharmacology and Therapeutics Lecture Notes provides a clear and accessible overview of all the key prescribing topics needed for medical finals and beyond. Detailed coverage and discussion of pharmacology in a clinical context, combined with an easy-to-understand, readable style, helps improve and test understanding of pharmacological principles and reasoning on rotation and into the foundation years. Key features for this edition include: • Clinical scenarios to root each chapter firmly in a real-life setting • Prescribing points flagging up important issues of clinical relevance • Expanded sections on drugs you may need in a hurry, prescribing and its pitfalls, and paediatric prescribing • A self-assessment section to test your knowledge and help prepare for examinations Clinical Pharmacology and Therapeutics Lecture Notes is an ideal resource for all medical students, junior doctors, and other prescribers, whether learning how pharmacological principles relate to clinical situations, brushing up on the basics while on rotation, or looking for a comprehensive overview of prescribing and therapeutics.
Delicious recipes and expert cooking tips for diabetics Having diabetes doesn't mean having to abandon great food. Diabetes Cookbook For Canadians For Dummies, Updated Edition offers an abundance of delicious recipes that will help diabetics and prediabetics enjoy meals and manage their diabetes. Based on the most recent edition of the Clinical Practice Guidelines for Diabetes Management, this new cookbook includes over 100 additional recipes and updated coverage on the latest drugs for diabetes management and new guidelines for target blood glucose levels. Diabetes Cookbook For Dummies offers valuable information for diabetics and anyone who cooks for diabetics. The authors offer meal planning suggestions, shopping tips, and even plot out a month of diverse and unexpected menus, including mouth-watering full-color photos of some of the delicious meals. Learn to cook meals you love that will comply with proper diabetes management Expand your culinary range with new interpretations of traditional dishes Make managing your diabetes more enjoyable with exciting menu options Learn how to make meal planning and preparation part of your daily routine This updated cookbook, a companion to the bestselling Diabetes For Canadians For Dummies, 3rd Edition offers delicious and easy-to-prepare recipes that will help readers manage their diabetes.
Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter authored by pioneers in that field, making for a broad appeal to the chemical and biological scientists and technologists involved in drug discovery and development.
The straight facts on treating diabetes successfully With diabetes now considered pandemic throughout the world, there have been enormous advances in the field. Now significantly revised and updated, this new edition of Diabetes For Dummies includes the latest information on diabetes medications and monitoring equipment, new findings about treating diabetes in the young and elderly, new ways to diagnose and treat long- and short-term complications, updated nutritional guidelines, new tools for measuring blood sugar and delivering insulin to the body, and much more. There's no question that the burden of diabetes is increasing globally: it's estimated that 387 million people worldwide are living with diabetes, and that staggering number is expected to increase an additional 205 million+ by 2035. If you or a loved one is part of this overwhelming statistic, you can take comfort in the sensitive and authoritative information provided in this hands-on guide. From monitoring and maintaining your glucose to understanding the importance of exercising and eating right—and everything in between—Diabetes For Dummies takes the guesswork out of living with diabetes and empowers you to take control and keep your life on a healthy track. Reduce your risk of diabetes complications Discover the latest and the tried-and-true options for monitoring blood sugar Get up to speed on the various diabetes medications and lifestyle strategies Improve diabetes control and overall health If you're one of the millions of diabetics or pre-diabetics in search of an accessible and up-to-date resource to help you manage this disease, Diabetes For Dummies is the trusted guide you'll turn to again and again.