Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's «Toxicity Testing in the 21st Century: A Vision and Strategy» and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing. High-Throughput Screening Methods in Toxicity Testing is divided into five parts: General aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profiling Assessing different cytotoxicity endpoints Assessing DNA damage and carcinogenesis Assessing reproductive toxicity, cardiotoxicity, and haematotoxicity Assessing drug metabolism and receptor-related toxicity Each chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined. Throughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods. This book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.
Тест для аквариумной воды Sera Nitrite-Test NO2 специальное средство для начинающих и уже опытных аквариумистов. Используется для определения содержания нитритов в пресноводном аквариуме. Чтобы не ошибиться в пропорциях внимательно прочитайте инструкцию. От качества воды зависит жизнь и здоровье рыбок, а также общее состояние аквариума. Поэтому надо хорошенько изучите все детали влияющие на качество аквариумной воды.
Тест для аквариумной воды Sera Nitrite-Test NO3 специальное средство для начинающих и уже опытных аквариумистов. Используется для определения содержания нитратов в пресноводном аквариуме. Чтобы не ошибиться в пропорциях внимательно прочитайте инструкцию. От качества воды зависит жизнь и здоровье рыбок, а также общее состояние аквариума. Поэтому надо хорошенько изучите все детали влияющие на качество аквариумной воды.
An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Now you can score higher in chemistry Every high school requires a course in chemistry for graduation, and many universities require the course for majors in medicine, engineering, biology, and various other sciences. U Can: Chemistry I For Dummies offers all the how-to content you need to enhance your classroom learning, simplify complicated topics, and deepen your understanding of often-intimidating course material. Plus, you'll find easy-to-follow examples and hundreds of practice problems—as well as access to 1,001 additional Chemistry I practice problems online! As more and more students enroll in chemistry courses,, the need for a trusted and accessible resource to aid in study has never been greater. That's where U Can: Chemistry I For Dummies comes in! If you're struggling in the classroom, this hands-on, friendly guide makes it easy to conquer chemistry. Simplifies basic chemistry principles Clearly explains the concepts of matter and energy, atoms and molecules, and acids and bases Helps you tackle problems you may face in your Chemistry I course Combines 'how-to' with 'try it' to form one perfect resource for chemistry students If you're confused by chemistry and want to increase your chances of scoring your very best at exam time, U Can: Chemistry I For Dummies shows you that you can!
Zebrafish: Methods for Assessing Drug Safety and Toxicity offers a practical guide for using zebrafish as a tool for toxicology studies. Consolidating key protocols and approaches to help researchers navigate the important and evolving field of zebrafish models for toxicity screening, this new title describes the methods for using the zebrafish as a model organism to assess compound-induced toxicity on all major organs. Individual chapters that concentrate on assays for each organ system are included and various analytical tools including microscopy, microplate readers, high content imaging systems, ECG, blood pressure monitors, high speed video and motion detectors are described.
The MCAT is undergoing major changes in early 2015. The test itself will be almost twice as long as its prior incarnation, and future medical students will want even more assistance preparing for this daunting new exam. MCAT Organic Chemistry Review will help them prepare for the organic chemistry material on revised test. The book provides thorough topic reviews of all the general chemistry students need to know, including structures and bonding, substitution and elimination reactions, electrophilic addition reactions, nucleophilic addition and cycloaddition reactions, lab techniques and spectroscopy, and biologically important organic chemistry.
Physical Inorganic Chemistry contains the fundamentals of physical inorganic chemistry, including information on reaction types, and treatments of reaction mechanisms. Additionally, the text explores complex reactions and processes in terms of energy, environment, and health. This valuable resource closely examines mechanisms, an under-discussed topic. Divided into two sections, researchers, professors, and students will find the wide range of topics, including the most cutting edge topics in chemistry, like the future of solar energy, catalysis, environmental issues, climate changes atmosphere, and human health, essential to understanding chemistry.
Discover the science of beer and beer making Ever wondered just how grain and water are transformed into an effervescent, alcoholic beverage? From prehistory to our own time, beer has evoked awe and fascination; it seems to have a life of its own. Whether you're a home brewer, a professional brewer, or just someone who enjoys a beer, The Chemistry of Beer will take you on a fascinating journey, explaining the underlying science and chemistry at every stage of the beer making process. All the science is explained in clear, non-technical language, so you don't need to be a PhD scientist to read this book and develop a greater appreciation for the world's most popular alcoholic drink. The Chemistry of Beer begins with an introduction to the history of beer and beer making. Author Roger Barth, an accomplished home brewer and chemistry professor, then discusses beer ingredients and the brewing process. Next, he explores some core concepts underlying beer making. You'll learn chemistry basics such as atoms, chemical bonding, and chemical reactions. Then you'll explore organic chemistry as well as the chemistry of water and carbohydrates. Armed with a background in chemistry principles, you'll learn about the chemistry of brewing, flavor, and individual beer styles. The book offers several features to help you grasp all the key concepts, including: Hundreds of original photographs and line drawings Chemical structures of key beer compounds Glossary with nearly 1,000 entries Reference tables Questions at the end of each chapter The final chapter discusses brewing at home, including safety issues and some basic recipes you can use to brew your own beer. There's more to The Chemistry of Beer than beer. It's also a fun way to learn about the science behind our technology and environment. This book brings life to chemistry and chemistry to life.
Trace elements occur naturally in soils and some are essential nutrients for plant growth as well as human and animal health. However, at elevated levels, all trace elements become potentially toxic. Anthropogenic input of trace elements into the natural environment therefore poses a range of ecological and health problems. As a result of their persistence and potential toxicity, trace elements continue to receive widespread scientific and legislative attention. Trace Elements in Soils reviews the latest research in the field, providing a comprehensive overview of the chemistry, analysis, fate and regulation of trace elements in soils, as well as remediation strategies for contaminated soil. The book is divided into four sections: • Basic principles, processes, sampling and analytical aspects: presents an overview including general soil chemistry, soil sampling, analysis, fractionation and speciation. • Long-term issues, impacts and predictive modelling: reviews major sources of metal inputs, the impact on soil ecology, trace element deficient soils and chemical speciation modelling. • Bioavailability, risk assessment and remediation: discusses bioavailability, regulatory limits and cleanup technology for contaminated soils including phytoremediation and trace element immobilization. • Characteristics and behaviour of individual elements Written as an authoritative guide for scientists working in soil science, geochemistry, environmental science and analytical chemistry, the book is also a valuable resource for professionals involved in land management, environmental planning, protection and regulation.
Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison – and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia – it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: chemistry of As, Sb and Bi biological chemistry of arsenic biological chemistry of Sb and Bi arsenic and antimony speciation in environmental and biological samples arsenic in traditional chinese medicine arsenic in aquifers biomethylation of As, Sb and Bi uptake of metalloids by cells bismuth complexes of porphyrins and their potential in medical applications Helicobacter pylori and bismuth metabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patients anticancer properties of As, Sb and Bi radio-Bi in cancer therapy genotoxicity of As, Sb and Bi metallomics as a new technique for As, Sb and Bi metalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.
If you are a parent struggling to help your child with chemistry homework, this is a short book that will help you. It covers key chemistry topics: Oxides, Bases, Acids, Salts, Equivalent proportions, Acid Base reactions, Weight and Volume problems, Equilibrium, Le Chatelier’s Principle, Freezing and Boiling points, Balance Redox Reactions, Stoichiometry (with answers and solutions).If you are student, read this book and you will prove to yourself that you can understand chemistry!
Practice makes perfect—and helps deepen your understanding of chemistry Every high school requires a course in chemistry, and many universities require the course for majors in medicine, engineering, biology, and various other sciences. 1001 Chemistry Practice Problems For Dummies provides students of this popular course the chance to practice what they learn in class, deepening their understanding of the material, and allowing for supplemental explanation of difficult topics. 1001 Chemistry Practice Problems For Dummies takes you beyond the instruction and guidance offered in Chemistry For Dummies, giving you 1,001 opportunities to practice solving problems from the major topics in chemistry. Plus, an online component provides you with a collection of chemistry problems presented in multiple-choice format to further help you test your skills as you go. Gives you a chance to practice and reinforce the skills you learn in chemistry class Helps you refine your understanding of chemistry Practice problems with answer explanations that detail every step of every problem Whether you're studying chemistry at the high school, college, or graduate level, the practice problems in 1001 Chemistry Practice Problems For Dummies range in areas of difficulty and style, providing you with the practice help you need to score high at exam time.
A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies.
Chemistry For Dummies, 2nd Edition (9781119293460) was previously published as Chemistry For Dummies, 2nd Edition (9781118007303). While this version features a new Dummies cover and design, the content is the same as the prior release and should not be considered a new or updated product. See how chemistry works in everything from soaps to medicines to petroleum We're all natural born chemists. Every time we cook, clean, take a shower, drive a car, use a solvent (such as nail polish remover), or perform any of the countless everyday activities that involve complex chemical reactions we're doing chemistry! So why do so many of us desperately resist learning chemistry when we're young? Now there's a fun, easy way to learn basic chemistry. Whether you're studying chemistry in school and you're looking for a little help making sense of what's being taught in class, or you're just into learning new things, Chemistry For Dummies gets you rolling with all the basics of matter and energy, atoms and molecules, acids and bases, and much more! Tracks a typical chemistry course, giving you step-by-step lessons you can easily grasp Packed with basic chemistry principles and time-saving tips from chemistry professors Real-world examples provide everyday context for complicated topics Full of modern, relevant examples and updated to mirror current teaching methods and classroom protocols, Chemistry For Dummies puts you on the fast-track to mastering the basics of chemistry.