The Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. This book explains the aetiology, pathogenesis and clinical treatment of all risk factors as well as the relationship with diabetes, non alcoholic fatty liver disease, polycystic ovary syndrome and coronary heart disease. The Metabolic Syndrome has been further improved from the 1st edition that was highly commended in 2006 Annual British Medical Association medical books competition. All chapters from the first edition are fully updated and this new edition contains an increase in international contributions and five new chapters on: Childhood obesity and metabolic syndrome Bariatric surgery for obesity Fitness Brain insulin resistance and appetite The nature of the insulin resistance seen in metabolic syndrome. This brand new edition of The Metabolic Syndrome will be an indispensable resource for all clinical researchers, physicians and scientists requiring detailed up-to-date information on the metabolic syndrome to further their own research or to treat and manage the syndrome and its complications. Specifically, the text will be of particular relevance to those involved and working in the fields of diabetes, endocrinology, obesity, cardiology, vascular disease and hepatology.
This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, then expanding the discussion to diseases associated with metabolic syndrome. The development of drug therapies for these diseases and complications is extensively covered. The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications.
Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids provides current research exploring the links among insulin, insulin receptors, polyunsaturated fatty acids, brain growth and disease. Specific interactions of essential fatty acids and polyunsaturated fatty acids in brain development and several disease groups are described. The role of inflammation in disease and how fatty acids regulate low-systemic inflammation are examined and explained. Metabolic and neurologic dynamics are presented to provide a linkage between the presence of omega-3 and omega-6 and protection against diseases and conditions such as diabetes mellitus, obesity, autoimmune diseases and hypertension.
The relationship of metabolic diseases to cardiovascular disease (CVD) is reaching epidemic proportions. This relates mostly to the increasing prevalence of obesity, the metabolic syndrome and type 2 diabetes. This book outlines and addresses the metabolic factors and related diseases that contribute to CVD, including brief introductions to metabolic pathways including lipid and lipoprotein metabolism, macronutrient fuel partitioning, insulin action and body weight regulation. Mechanisms that relate to becoming obese, maintenance of the obese state, the dyslipidemias, and glucose intolerance/diabetes are also addressed, and the importance of interventions that reduce metabolic risk factors and CVD are covered.
Amino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the incorporation of inorganic nitrogen into amino acids, the book then details other major nitrogenous compounds in micro-organisms, plants and animals. Contents include a discussion of the catabolism of amino acids and other nitrogenous compounds in animals, and the microbiological reactions involved in release of nitrogen gas back into the atmosphere. Mammalian (mainly human) protein and amino acid requirements are considered in detail, and the methods that are used to determine them. Chapters consider individual amino acids, grouped according to their metabolic origin, and discussing their biosynthesis (in plants and micro-organisms for those that are dietary essentials for human beings), major metabolic roles (mainly in human metabolism) and catabolism (again mainly in human metabolism). There is also discussion of regulatory mechanisms for all these metabolic pathways, and of metabolic and genetic diseases affecting the (human) metabolism of amino acids. Throughout the book the emphasis is on the nutritional importance of amino acids, integration and control of metabolism and metabolic and other disturbances of relevance to human biochemistry and health. Completely revised edition of this comprehensive text covering all the latest findings in amino acid metabolism research Written by an authority in the field Covers new advances in structural biology Clear illustrations of all structures and metabolic pathways Full list of recommended further reading for each chapter and bibliography of papers cited in the text
Praise for Doing Therapy with Children and Adolescents with Asperger Syndrome «Providing an explanation of Asperger's based on a review of scientific research, Richard Bromfield describes how the characteristics of the syndrome affect the person's thoughts and experiences throughout childhood. Psychotherapy based on the practices described in this book will change the destiny of children and adults with Asperger Syndrome to one of greater connectivity to themselves and others. This should become the primary text for pshchotherapists working with children and adolescents with Asperger's.» —Tony Attwood, PhD, author of The Complete Guide to Asperger's Syndrome «Dr. Blomfield generously shares his wisdom and experience in this very accessible, honest, and often moving book. Any clinician who reads it in its entirely—or even selects a chapter or two at random—will no doubt discover new paths to take their most complex and challenging clients and gain a greater appreciation for those with Asperger Syndrome. Bromfield gives us all a window into a world that is hard to describe, impossible to imagine, but needs and deserves to be understood.» —Naomi Angoff Chedd, LMHC, Autism Specialist and coauthor of Replays Cutting-edge guidance for effective treatment of children and adolescents with Asperger Syndrome Diagnoses of Asperger Syndrome in children and adolescents are on the rise, and while some clinicians have training and experience in this area, most do not. Using vivid case material, Doing Therapy with Children and Adolescent with Asperger Syndrome offers clinicians the guidance they need to treat the young people they endeavor to help.
Asperger's Syndrome For Dummies covers everything that both people living with the condition and their families need to know. From explaining symptoms and getting a diagnosis, through to overcoming bullying in schools and choosing between the therapy and medical treatments available, this is a complete guide to surviving and thriving with the condition. Asperger's Syndrome For Dummies includes: Part I: Understanding Asperger's syndrome (AS) Chapter 1: Introducing Asperger's syndrome Chapter 2: Discovering the causes of Asperger's syndrome Chapter 3: Diagnosing Asperger's syndrome Part II: Living with Asperger's syndrome Chapter 4: Enjoying Life with Asperger's Chapter 5: Getting the most out of education and the workplace Chapter 6: Finding independence and advocating for your rights Part III: Supporting people with Asperger's syndrome Chapter 7: Parenting and Asperger's syndrome Chapter 8: Relating to adults with Asperger's syndrome Chapter 9: Creating an AS friendly environment Part IV: Discovering therapies, medication, diet and environments for AS Chapter 10: Navigating Behavioural Therapies for Asperger's Syndrome Chapter 11: Understanding medication and diet in Asperger's syndrome Part V: Part of Tens Chapter 12: Ten Organisations to go for help and information Chapter 13: Ten positives about living with Asperger's Chapter 14: Ten famous people who probably had Asperger's
Beverly Engel brings her expertise to this important examination of the Jekyll and Hyde Syndrome—the first book to address this abusive syndrome. She discusses the origins of the disorder, names its seven major manifestations, explains how to identify Jekyll and Hyde behavior in other people and in oneself, and outlines clear steps for how to heal Jekyll and Hyde tendencies for good.
Practical advice and information for living with Polycystic Ovarian Syndrome Polycystic Ovary Syndrome (PCOS) is a condition in which there is an imbalance of a woman's female sex hormones, and affects an estimated 10% of all women. This hormone imbalance may cause changes in the menstrual cycle, acne, small cysts in the ovaries, difficulty conceiving, high blood pressure, and other problems. It is treatable, but not curable, and sufferers have to rely on themselves for the long-term management of their condition. If you're living with PCOS, this guide gives you the latest information concerning treatments and research into Polycystic Ovarian Syndrome. PCOS For Dummies gives you a practical, plain-English guide to living with and managing Polycystic Ovarian Syndrome. In addition to providing valuable information concerning the causes and symptoms of Polycystic Ovarian Syndrome, PCOS For Dummies gives you the facts about the various treatment options that are available, including both traditional medical treatments and alternative therapies. Discusses the causes and symptoms of PCOS Advice for dealing with this disorder Covers the treatments and medicine available in the United States PCOS For Dummies is an invaluable resource for the millions who are suffering from this condition.
Do you manage patients with irritable bowel syndrome? Need a practical tool to guide you through best patient care and management? If so, this is the book for you. Highly practical, expertly-written, and packed with handy text tools like case histories, pitfall boxes and management algorithms, this attractive and convenient manual provides you with complete clinical guidance to irritable bowel syndrome (IBS), one of the most common GI conditions that doctors face daily. With contributions from the world’s leading experts in IBS and edited by a stellar editor team, inside you’ll find: A comprehensive symptom-specific approach to treatment options Strong emphasis on the clinical care and management of patients Exploration of the interface between primary and secondary care for IBS sufferers Self-assessment MCQs to improve clinical skills Examination of the overlap and difference between the USA and Europe in the management of IBS Perfect for doctors in primary care as well as gastroenterologists of all levels, Irritable Bowel Syndrome: Diagnosis and Clinical Management is the ideal consultation tool for the management of this extremely prevalent condition.
Up-to-date, reliable information about Tourette Syndrome and related disorders for teachers and parents Children with TS are often teased and punished for the unusual yet uncontrollable symptoms of their disorder. Academic failure is common. The Tourette Syndrome/OCD Checklist helps parents and teachers to better understand children and youth with TS and/or OCD and provide the support and interventions these children need. Presented in a simple, concise, easy-to-read checklist format, the book is packed with the latest research, practical advice, and information on a wide range of topics. Provides a wealth of information on Tourette Syndrome, Obsessive-Compulsive Disorder, and related conditions Includes strategies for discipline and behavior management, advice on supporting and motivating kids with TS and OCD, homework tips, and more Shows how to educate peer students about TS and OCD Loaded with practical information, strategies, and resources, this book helps parents and teachers to better understand Tourette Syndrome and OCD and shows how every individual can reach their potential in school and in life.
Working with principles from the fields of evolutionary and developmental biology (evo-devo), this fascinating work offers a new approach to analyzing child growth and development, examining each stage and transition in detail, from fetal development to preadulthood. Based on the author's in-depth review of the current literature and his own observations as a pediatric endocrinologist, the book demonstrates how the transitions between human life history phases represent unique periods of evolutionary adaptive response to the environment. In addition, the author explains why an understanding of these transition periods enables us to better understand the sequence and mechanisms of child growth as well as to better diagnose child growth disorders. Logically organized and clearly written, Evo-Devo of Child Growth: Sets a solid foundation of principles such as evolutionary thinking in medicine and child growth, life history theory, and heterochrony and allometry Examines the relationship between child growth and the theory of life history Applies evo-devo theory to fetal growth, infancy, childhood, juvenility, adolescence, and preadulthood Explores the trade-offs and adaptive phenotypic plasticity during transition periods Explains the role of life history theory in understanding and diagnosing growth disorders such as Down syndrome, Noonan syndrome, and Silver-Russell syndrome In addition to the author's own analysis and observations, this book also features notes from leading clinicians and evolutionary biologists, offering additional perspectives on the relationship between evo-devo and child growth and development. Evo-Devo of Child Growth provides a new perspective for evolutionary biologists to understand the phases and transitions of child growth. Moreover, it offers a new approach to help clinicians to better understand and diagnose a broad range of child growth disorders.
The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “… highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)