Bachelor Thesis from the year 2012 in the subject Business economics - Personnel and Organisation, grade: A+, , course: Human Resources Management, language: English, abstract: This thesis was aiming at examining the impact of workforce reduction on surviving employees in Egyptian organization post 25th January Revolution.This present study aims at investigating the impact of downsizing on organizational survivors in the Egyptian organization. It aims at unleashing the impact of procedural justice on symptoms of survivor syndrome. It was hypothesized that higher levels of perceived procedural justice leads to higher levels of organizational attachment, less levels of voluntary turnover. To answer proposed research questions, a mix of quantitative and qualitative methods was implemented to determine the impact of procedural justice on symptoms of survivor syndrome. The results obtained from the sample (N=101) survivors supported previous hypotheses and reflected the fact that when survivors perceive layoffs to be unfairly implemented, they suffer from high symptoms of survivor syndrome.
Doctoral Thesis / Dissertation from the year 2015 in the subject Medicine - Human Genetics, grade: 1, University of Rome "La Sapienza" (University of Rome "La Sapienza"), course: Clinical Immunology, language: English, abstract: Vici syndrome is a complex multisystem disorder characterized by congenital malformations of the brain, cataracts, skin hypopigmentation, progressive damage of cardiac function and muscle, immune deficiency. Affected children do not respond to vaccination, have low levels of antibodies in the blood and suffering from severe and frequent infections. The disease is caused by a mutation of the gene EPG5, which encodes a protein essential for the trafficking and function of intracellular vesicles. Cells use vesicles to eliminate uwanted material and remove dead cells. The unwanted material is incorporated into a vesicle and then merged with lysosomes containing proteins that digest the contents to be eliminated (autophagy). This system is essential already during the embryonic stage and then for life. Therefore, its failure causes a disease involving various organs and systems. Since infections are frequent in patients with Vici Syndrome, we think that EPG5 plays a role in the immune system:In this project i propose to assess whether EPG5 is necessary for cells to capture and degrade microorganisms and foreign particles, a necessary step to start the immune reaction. To do this i use cells from patients and healthy controls with fluorescen...
Cardiovascular disease is today the largest single contributor to global mortality. A major challenge in human health over the next 50 years is to reduce the impact of chronic diseases. The health benefits of a diet rich in fruits, vegetables and legumes have been well recognized. Poor compliance to dietary recommendations, unhealthy lifestyle and mismanagement of cardiovascular emergencies reflect the dearth of awareness among the community. This book provides data on the nutritional, cardiovascular and biochemical profile of adults living with cardiovascular disease in the 'Temple Town' of Tamil Nadu, Madurai with lucid and interesting illustrations. An attempt has been made to associate these factors along with their critical energy balance with cardiovascular disease. Specific focus has also been on the occurrence of various metabolic syndrome components and cardiovascular disease. This book can adorn the bookshelf of academicians, researchers, nutritionists and scholars interested in clinical nutrition.
Livestock has a great significance in the development of economic conditions of a country. In Pakistan the share of Livestock sector is approximately 53.2 percent in the agriculture value and 11.4 percent in national GDP during 2009-10. While other development sector experienced saturation and decline, there is trend in increase of livestock population in 2009-10. Total number of buffaloes and cattle is 30.8 and 34.3 millions respectively in Pakistan (Anonymous, 2009-10). The number of buffaloes and cattle is 14.4 and 17.8 millions respectively in Punjab province (Anonymous, 2006). Punjab is a home of highly specialized tropical/subtropical buffaloes and cattle breeds. Those animals suffer from a number of diseases. Ketosis is one of them , define as metabolic disorder and it is managmental influenced cows disease during the early lactation period.
Protein carbonylation has attracted the interest of a great number of laboratories since the pioneering studies at the Earl Stadtman’s lab at NIH started in early 1980s. Since then, detecting protein carbonyls in oxidative stress situations became a highly efficient tool to uncover biomarkers of oxidative damage in normal and altered cell physiology. In this book, research groups from several areas of interest have contributed to update the knowledge regarding detection, analyses and identification of carbonylated proteins and the sites where these modifications occur. The scientific community will benefit from these reviews since they deal with specific, detailed technical approaches to study formation and detection of protein carbonyls. Moreover, the biological impact of such modifications in metabolic, physiologic and structural functions and, how these alterations can help understanding the downstream effects on cell function are discussed. Oxidative stress occurs in all living organisms and affects proteins and other macromolecules: Protein carbonylation is a measure of oxidative stress in biological systems Mass spectrometry, fluorescent labelling, antibody based detection, biotinylated protein selection and other methods for detecting protein carbonyls and modification sites in proteins are described Aging, neurodegenerative diseases, obstructive pulmonary diseases, malaria, cigarette smoke, adipose tissue and its relationship with protein carbonylation Direct oxidation, glycoxidation and modifications by lipid peroxidation products as protein carbonylation pathways Emerging methods for characterizing carbonylated protein networks and affected metabolic pathways
Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy, nephropathy, peripheral neuropathy and blindness. The purpose of this study is to model the dynamic of the short-term glucose regulatory system (GRS) in man and its hormonal regulation by considering all the feedback loops which are responsible of controlling the glucose metabolism in man. The model proposed in this work used the system dynamics (SD) approach which was designed for studying complex systems. This SD model consists of twenty-three negative (balance) loops and six compartments. The model was validated during wide range of clinical test inputs, to be sure that this model accurately represents the really endocrine system. Understanding the mechanism underlying glucose-insulin oscillations and determination of the origin of the glucose-insulin levels oscillations is another purpose of this model. Other applications for this model also have been explored.
The author was born in Bristol, UK in 1960. She has two sons who were diagnosed autistic at an early age. She was diagnosed as having Asperger's Syndrome herself in 2001. In this book she attempts to explain her experiences as a carer and someone who has an autistic spectrum condition. Her aim is to help others think better of autistic people, to consider the way they are taught to belong to the world, and to suggest some possible solutions to problems facing them. Endorsement: "As a teacher of ICT in a Specialist College for the past seven years, I would recommend this book not only to fellow teachers but to parents or carers who come into contact with people who live with Autistic Spectrum Disorders(ASD)." MRS KC Kelly-Markwick, Oakwood Court College
Increasing fiber consumption can address, and even reverse the progression of pre-diabetes and other associated non-communicable diseases. Understanding the link between plant dietary fiber and gut health is a small step in reducing the heavy economic burden of metabolic disease risks for public health. This book provides an overview of the occurence, significance and factors affecting dietary fiber in plant foods in order to critically evaluate them with particular emphasis on evidence for their beneficial health effects.
Xenia Shantсeva wrote this story to inform more people about this syndrome. Do you like to sleep and dream? Not all people can sleep. Why? Aksinia will inform you about Restless legs syndrome. She will show the path of pain to science. Read the book and find the answer together.
Scientific Essay from the year 2008 in the subject Medicine - Internal Medicine, , language: English, abstract: This paper examines the relations between Apoliprotein B, Apoliprotein A1 and Diabetes Type 2.Diabetes mellitus refers to a group of metabolic disorders of multiple aetiology and characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. The effects of diabetes mellitus include long-term damage, dysfunction and failure of various organs. Diabetes mellitus may present with characteristic symptoms such as thirst, polyuria, blurring of vision, and weight loss. In its most severe forms, ketoacidosis or a non-ketotic hyperosmolar state may develop and lead to stupor, coma and in absence of effective treatment, death. Often symptoms are not severe, or may be absent, and consequently hyperglycaemia sufficient to cause pathological and functional changes may be present for a long time before the diagnosis is made. It is a major health problem in all nations. Diabetes is the single, most important metabolic disease, widely recognized as one of the leading causes of death and disability worldwide. This devastating disease can affect nearly every system in the body. It can cause blindness, lead to end stage renal disease, lower extremity amputations and increase the risk for stroke, ischemic heart disease, peripheral vascular disease, and neuropathy. Diabetic macro ...
Type 2 diabetes mellitus (T2DM) is a chronic, progressive metabolic disease characterized by chronic hyperglycemia. Although its main physiological abnormalities are insulin resistance and impaired insulin secretion, the specific underlying determinants of these metabolic defects remain uncertain. There are complex interactions between genetic, epigenetic, environmental and behavioral factors that contribute to the development of diabetes. Non-pharmacological and pharmacological interventions have been used for diabetic management. Over the past few years, research has started to focus on the use of novel adjuvant drugs as antioxidants and anti-inflammatory drugs for better management, as it was revealed that both oxidative stress and inflammation play a critical role in the disease pathogenesis.Thus, the development of antidiabetic drugs that can reverse insulin resistance is a potential therapeutic target. Although antidiabetic drugs may be effective in improving glycemic control, they do not appear to be effective in entirely preventing the progression of pancreatic ß-cells damage mediated by chronic hyperglycemia-induced decline in intracellular antioxidants. Therefore, antioxidant and anti-inflammatory therapy should be considered as an adjunct to the commonly used oral antidiabetics
My name is Joshua Fawcett, I am 15 years old and I was diagnosed with Aspergers Syndrome at the age of 4. I have always had a keen interest in the local history of my hometown of Scarborough. I hope you enjoy looking at the photos and information in my book as much as I have enjoyed producing it.
A comprehensive guide to help you understand why we put on weight! Dr Dawn explains our dietary needs at different stages of life, how metabolism differs, and the implications for our general health and wellbeing. There is a sensible look at the role of diet and exercise. Dr Dawn describes how even modest weight loss can affect your risk of developing other illnesses such as heart disease, and even how long you can expect to live. There is a comprehensive chapter on diabetes, including the types of diabetes and what we mean by terms like insulin resistance and metabolic syndrome.
Introduces readers to the growing applications of nutraceuticals and other natural product derivatives This comprehensive book presents a prophylactic and therapeutic approach to chronic disease prevention strategy by highlighting the translational potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies. It also shares the experiences of highly reputed experts working in the area of phytomedicine and nutraceutical agents in chemoprevention, to promote the significance of natural products and dietary factors as an elite priority for containing chronic diseases in the human population. Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery starts by examining natural food sources for the control of glycemia and the prevention of diabetic complications. It then looks at the anti-aging effects of sulfur-containing amino acids and nutraceuticals, and the potential of garcinia fruits to combat metabolic syndrome. Other topics covered include honey- and propolis-mediated regulation of protein networks in cancer cells; recent trends in drug discovery against Alzheimer’s disease; the therapeutic potential of metalloherbal nanoceuticals; and much more. Offers an alternative, natural approach to the prevention of chronic diseases Emphasizes the potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies Features contributions from world-renowned experts in the field of phytomedicine and nutraceutical agents in chemoprevention Includes prevention strategies in normal/risk populations through routine inclusion of specific dietary regimens and as therapeutic strategy for better management through adjuvant interventions with conventional treatment protocols Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery will appeal to graduate students and professionals in cell and molecular biology, translational research, pharmacology/drug discovery, medicinal chemistry, and clinical nutrition.
Aide to the United States Military. his own words, Fahdl recounts his story of going from life as a twenty-one-year-old, upper-middle class student at the University of Baghdad to being recruited right off his neighborhood streets to serve as an interpreter for a United States Army unit just days after the fall of Saddam Hussein’s regime. Over the next two years, Fahdl goes on to translate for U.S. drill sergeants training new Iraqi Army recruits in Ramadi , serves alongside U.S. Marines during the first Battle of Fallujah, and eventually lands a position as a linguist with Iraq’s newly formed national intelligence agency in Baghdad. Along the way, he suffers combat injuries, faces the challenges of integrating with American soldiers in the U.S. camps, is hunted by local insurgency groups for assisting the ”infidels” and eventually falls in love with an American service member.Voicing the Eagle is a unique, firsthand perspective on one of the United States most controversial foreign conflicts.