The life of the Polish-French pianist and composer Frédéric Chopin (1810—1849) was, to a great extent, influenced by his disease. Nevertheless, the diagnosis and differential diagnoses of his suffering remain a matter of debates in numerous biographical studies on the composer’s life. This study shall conduct a systematization and overview of Chopin’s medical history, in an effort to outline pathways to his most probable diagnosis.
Полный вариант заголовка: «The doctrine of life for the New Jerusalem, from the commandements of the Decalogue / translated from the latin of Emanuel Swedenborg origanally published at Amsterdam in the year 1763».
This illuminating new volume will tell the stories of the people living in different coffee-producing communities around the world, through McCurry's beautifully arresting, colour photography. From the foothills of the Andes to the slopes of Kilimanjaro, vibrant full-colour images document the realities of life for the people working at the source of this familiar commodity. Far-ranging photographs from Colombia, Honduras, Peru, Brazil, Ethiopia, Tanzania, India and Vietnam include portraits of children, workers and everyday community life, alongside stunning natural landscapes.
Utilizing new primary source material from the Papers of George Washington, a documentary editing project dedicated to the transcription and publication of original documents, A Companion to George Washington features a collection of original readings from scholars and popular historians that shed new light on all aspects of the life of George Washington. Provides readers with new insights into previously neglected aspects of Washington's life Features original essays from top scholars and popular historians Based on new research from thousands of previously unpublished letters to and from Washington
Honorable mention – Biomedicine and Neuroscience, 2011 Prose Awards An examination of how the cell should be described in order to effectively process biological data «The fruitful pursuit of biological knowledge requires one to take Einstein's admonition [on science without epistemology] as a practical demand for scientific research, to recognize Waddington's characterization of the subject matter of biology, and to embrace Wiener's conception of the form of biological knowledge in response to its subject matter. It is from this vantage point that we consider the epistemology of the cell.» —from the Preface In the era of high biological data throughput, biomedical engineers need a more systematic knowledge of the cell in order to perform more effective data handling. Epistemology of the Cell is the first authored book to break down this knowledge. This text examines the place of biological knowledge within the framework of science as a whole and addresses issues focused on the specific nature of biology, how biology is studied, and how biological knowledge is translated into applications, in particular with regard to medicine. The book opens with a general discussion of the historical development of human understanding of scientific knowledge, the scientific method, and the manner in which scientific knowledge is represented in mathematics. The narrative then gets specific for biology, focusing on knowledge of the cell, the basic unit of life. The salient point is the analogy between a systems-based analysis of factory regulation and the regulation of the cell. Each chapter represents a key topic of current interest, including: Causality and randomness Translational science Stochastic validation: classification Stochastic validation: networks Model-based experimentation in biology Epistemology of the Cell is written for biomedical researchers whose interests include bioinformatics, biological modeling, biostatistics, and biological signal processing.
Axel Heyst, a dreamer and a restless drifter, believes he can avoid suffering by cutting himself off from others. Then he becomes involved in the operation of a coal company on a remote island in the Malay Archipelago, and when it fails he turns his back on humanity once more. But his life alters when he rescues a young English girl, Lena, from Zangiacomo's Ladies' Orchestra and the evil innkeeper Schomberg, taking her to his island retreat. The affair between Heyst and Lena begins with her release, but the relationship shifts as Lena struggles to save Heyst from the detachment and isolation that have inhibited and influenced his life. Victory is both a tale of rescue and adventure and a perceptive study of a complex relationship and of the power of love.
Human blood performs many important functions including defence against disease and transport of biomolecules, but perhaps the most important is to carry oxygen – the fundamental biochemical fuel – and other blood gases around the cardiovascular system. Traditional therapies for the impairment of this function, or the rapid replacement of lost blood, have centred around blood transfusions. However scientists are developing chemicals (oxygen therapeutics, or “blood substitutes”) which have the same oxygen-carrying capability as blood and can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development. The first part of the book deals with the chemistry, biochemistry, physiology and toxicity of oxygen, including chapters on hemoglobin reactivity and regulation; the major cellular and physiological control mechanisms of blood flow and oxygen delivery; hemoglobin and myoglobin; nitric oxide and oxygen; and the role of reactive oxygen and nitrogen species in ischemia/reperfusion Injury. The book then discusses medical needs for oxygen supply, including acute traumatic hemorrhage and anemia; diagnosis and treatment of haemorrhages in «non-surgical» patients; management of perioperative bleeding; oxygenation in the preterm neonate; ischemia normobaric and hyperbaric oxygen therapy for ischemic stroke and other neurological conditions; and transfusion therapy in β thalassemia and sickle cell disease Finally “old”and new strategies for oxygen supply are described. These include the political, administrative and logistic issues surrounding transfusion; conscientious objection in patient blood management; causes and consequences of red cell incompatibility; biochemistry of red blood cell storage; proteomic investigations on stored red blood cells; red blood cells from stem cells; the universal red blood cell; allosteric effectors of hemoglobin; hemoglobin-based oxygen carriers; oxygen delivery by natural and artificial oxygen carriers; cross-linked and polymerized hemoglobins as potential blood substitutes; design of novel pegylated hemoglobins as oxygen carrying plasma expanders; hb octamers by introduction of surface cysteines; hemoglobin-vesicles as a cellular type hemoglobin-based oxygen carrier; animal models and oxidative biomarkers to evaluate pre-clinical safety of extracellular hemoglobins; and academia – industry collaboration in blood substitute development. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood is an essential reference for clinicians, haematologists, medicinal chemists, biochemists, molecular biologists, biotechnologists and blood substitute researchers.
The best-selling book for teaching basic life skills, fully revised and updated This book offers teachers and parents a unique collection of 190 ready-to-use activities complete with student worksheets, discussion questions, and evaluation suggestions to help exceptional students acquire the basic skills needed to achieve independence and success in everyday life. Each of the book's activities focuses on specific skills within the context of real-life situations and includes complete teacher instructions for effective use, from objective and introduction through optional extension activities and methods to assess student learning. The book includes numerous reproducible parent letters which can be sent home to help parents reinforce these lessons while children are away from school. A revised and updated edition of the classic book for teaching basic life skills Includes 190 complete activities with reproducible worksheets, discussion questions, and evaluation suggestions for developing independence Offers ideas for developing practical skills to deal with identity theft, cell phone manners, budgeting, eating healthy meals, using credit cards, time management, and much more Mannix is the best-selling author of Social Skills Activities for Special Children, Writing Skills Activities for Special Children, and Character Building Activities for Kids
This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with the authors chosen from among the leaders in their respective fields. This volume represents an essential guide for students and researchers seeking an overview of the field.
Полный вариант заголовка: «Interesting account of the early voyages : made by the Portuguese, Spaniards, &. : to Affrica, East and West-Indies : the discovery of numerous Islands : with particulars of the Lives of those eminent navigators : including the life and voyages of Columbus : to which is perpixed the life of that great circumnavigator Captain Cook : with particulars of his death / extracted from Dr. Kipps's».
This highly original work introduces the ideas and arguments of the ancient Chinese philosophies of Confucianism and Daoism to some of the most intractable social issues of modern American life, including abortion, gay marriage, and assisted suicide. Introduces the precepts of ancient Chinese philosophers to issues they could not have anticipated Relates Daoist and Confucian ideas to problems across the arc of modern human life, from birth to death Provides general readers with a fascinating introduction to Chinese philosophy, and its continued relevance Offers a fresh perspective on highly controversial American debates, including abortion, stem cell research, and assisted suicide