Pathology of Small Mammal Pets presents a ready reference for veterinarians, veterinary pathologists, and technicians who work with small mammal companion animals. Provides up-to-date, practical information on common disease conditions in small mammal companion animals Offers chapters logically organized by species, with comprehensive information on diagnosing diseases in each species Takes a practical, system-based approach to individual disease conditions Covers clinical signs, laboratory diagnostics, gross pathology, histopathology, and differential diagnoses in detail Includes relevant information for conventional breeding operations and breeding facilities, with strategies for disease management in herds and colonies Features information on normal anatomy in included species to assist in recognizing pathology
Plant pathogens and diseases are among the most significant challenges to survival that plants face. Disease outbreaks caused by microbial or viral pathogens can decimate crop yields and have severe effects on global food supply. Understanding the molecular mechanisms underlying plant immune response and applying this understanding to develop biotechnological tools to enhance plant defense against pathogens has great potential for moderating the impact of plant disease outbreaks. Plant Pathogen Resistance Biotechnology’s main focus is an in depth survey of the biological strategies being used to create transgenic disease resistant plants for sustainable plant resistance Plant Pathogen Resistance Biotechnology is divided into four sections. The first section covers biological mechanisms underpinning disease resistance in plants, while the second highlights case studies of important pathogen-crop groups and then considers why the application of important pathogen-crop groups, transgenic-based strategies designed to selectively target pathogens could benefit crop production. The third section provides information on the status of transgenic crops around the world, and finally the last part explores high-tech alternatives to genetic engineering for developing disease resistant traits in plants. Edited and authored by leaders in the field, Plant Pathogen Resistance Biotechnology will be an invaluable resource to those studying or researching plant biotechnology, plant pathology, plant biology, plant and crop genetics, in addition to crop science.
While many high-income countries observe a relative decline in the population impact of heart disease and deal with the problem of an older patient population who readily survive earlier non-fatal encounters with the condition, Africa contends with a typically younger population with frequently advanced and often fatal heart disease. While high-income countries exclusively deal with non-communicable forms of heart disease, Africa contends with both communicable and non-communicable forms of heart disease. Designed to provide anyone with an interest in heart disease in Africa with an immediate sense of how the area is progressing from a clinical to research perspective in responding to this evolving epidemic Presents salient research uncovering the evolving burden of communicable and non-communicable forms of heart disease, Includes content on maternal heart disease, infant and childhood heart disease, risk and prevention, heart failure and other common forms of heart disease in rural and urban communities in Africa.
Advances in Intervertebral Disc Disease in Dogs and Cats defines our present knowledge of this common clinical problem, compiling information related to the canine and feline intervertebral disc into a single resource. As a comprehensive, focused work, the book is an authoritative reference for understanding and treating disc disease, providing a sound scientific and clinical basis for decision making. Offering an objective synthesis of the current literature, the book supplies guidance on the approach to a potential disc rupture, surgical and medical strategies, and management of the patient. Offering a complete understanding of intervertebral disc disease, the book describes and discusses the controversies and issues surrounding this topic, acknowledging the gaps in our knowledge. Advances in Intervertebral Disc Disease in Dogs and Cats presents up-to-date, reliable information on this common condition for veterinary surgeons, neurologists, and general practitioners.
Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states
Highly Commended at the British Medical Association Book Awards 2016 The third edition of Anesthesia for Congenital Heart Disease, the recognized gold-standard reference in this field, offers a major update and expansion of the textbook to reflect the ongoing development of the practice of pediatric and congenital cardiac anesthesia and the burgeoning knowledge base in this exciting field. Includes two new chapters addressing key areas; anesthetic and sedative neurotoxicity in the patient with congenital heart disease, and anesthesia in the patient with pulmonary hypertension Now in full color, with over 200 illustrations and photographs Multiple-choice questions accompany each chapter covering the most crucial learning points to optimize the learning experience for readers at all levels
Canine and Feline Anesthesia and Co-Existing Disease is the first book to draw together clinically relevant information on the anesthetic management of dogs and cats with existing disease conditions. Providing a detailed reference on avoiding and managing complications resulting from concurrent disease, the book offers a ready reference for handling anesthesia in patients with common presenting diseases. Organized by body system, Canine and Feline Anesthesia and Co-Existing Disease is designed to allow the reader to quickly find and apply advice for anesthetizing patients with specific conditions. Each chapter presents in-depth, practical information on the special considerations before, during, and after sedation and anesthesia of a patient with a given disease. Canine and Feline Anesthesia and Co-Existing Disease is a useful reference for general practitioners, veterinary students, specialists in a variety of areas, and veterinary anesthesiologists alike.
An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.
Infectious disease surveillance has evolved at an extraordinary pace during the past several decades, and continues to do so. It is increasingly used to inform public health practice in addition to its use as a tool for early detection of epidemics. It is therefore crucial that students of public health and epidemiology have a sound understanding of the concepts and principles that underpin modern surveillance of infectious disease. Written by leaders in the field, who have vast hands-on experience in conducting surveillance and teaching applied public health, Concepts and Methods in Infectious Disease Surveillance is comprised of four sections. The first section provides an overview, a description of systems used by public health jurisdictions in the United States and legal considerations for surveillance. The second section presents chapters on major program-area or disease-specific surveillance systems, including those that monitor bacterial infections, foodborne diseases, healthcare-associated infections, and HIV/AIDS. The following section is devoted to methods for conducting surveillance and also approaches for data analysis. A concluding section summarizes communication of surveillance findings, including the use of traditional and social media, in addition to showcasing lessons learned from the New York City Department of Health’s experience in surveillance and epidemiology training. This comprehensive new book covers major topics at an introductory to intermediate level, and will be an excellent resource for instructors. Suitable for use in graduate level courses in public health, human and veterinary medicine, and in undergraduate programs in public-health-oriented disciplines, Concepts and Methods in Infectious Disease Surveillance is also a useful primer for frontline public health practitioners, hospital epidemiologists, infection control practitioners, laboratorians in public health settings, infectious disease researchers, and medical and public health informaticians interested in a concise overview of infectious disease surveillance.
Identifying how, why and in whom gastrointestinal disease occurs, and what can be done to prevent it, is of key importance for the modern-day gastroenterologist and researcher. Brought to you by the world’s leading gastroenterologists, the second edition of GI Epidemiology: Diseases and Clinical Methodology is the only book that combines detailed analysis of the epidemiology of GI disease with a study of the methodology of clinical research. With a much greater clinical focus on the diagnostic and management approach for each disease than before, all existing chapters are fully updated with the very latest in statistical and clinical data. In addition, the revised edition contains several significant improvements, notably: • Five extra disease epidemiology chapters: Upper GI Bleeding; Hepatitis B and C; Common Tropical GI Diseases; Nutritional Epidemiology and GI Cancers; and Obesity among Adults • More illustrations, including maps of each disease • A more international focus with the inclusion of two experienced European editors • MCQs, summary checklists and key points throughout • Ten extra online-only chapters on methodological issues related to GI epidemiology such as Patient reported GI Epidemiology: Diseases and Clinical Methodology, 2nd Edition is the perfect reference tool for gastroenterologists involved in both patient management and clinical research, and also for epidemiologists involved specifically in GI disease data and more general epidemiological studies. Titles of Related Interest Yamada’s Handbook of Gastroenterology, 3rd Edition Yamada; ISBN 9780470656204 Essentials of Gastroenterology Friedman; ISBN 9780470656259
Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.